Scattered light and visual function in a randomized trial of deep lamellar endothelial keratoplasty and penetrating keratoplasty
Scattered light and visual function in a randomized trial of deep lamellar endothelial keratoplasty and penetrating keratoplasty
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DOI：
10.1016/j.ajo.2007.09.002
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发表时间：
2008-01-01
影响因子：
4.2
通讯作者：
Baratz, Keith H.
中科院分区：
文献类型：
--
作者：
Patel, Sanjay V.;Mclaren, Jay W.;Baratz, Keith H.
目的：比较深板层内皮角膜移植术 (DLEK) 和穿透性角膜移植术 (PK) 治疗内皮功能障碍时的视力、眼内前向光散射和角膜后向散射。设计：一项随机临床试验。方法：13 只眼（12 名患者）被随机分配至 DLEK，巩膜切口为 9 mm，15 只眼（14 名患者）被随机分配至 PK。主要结果是术后 12 个月的高对比度最佳眼镜矫正视力 (BSCVA)；术后 1、3、6 和 12 个月测量眼内前向光散射和角膜后向散射。结果：12 个月时的 BSCVA DLEK 为 0.34 +/- 0.16 logMAR（最小分辨率对数），PK 为 0.25 +/- 0.21 logMAR（P = .23；12 个月时的最小可检测差异为 0.23）日志MAR）。 DLEK 术后前向光散射的变化与 BSCVA 的变化相关（r = -0.66；P
PURPOSE: To compare vision, intraocular forward light scatter and corneal backscatter between deep lamellar endothelial keratoplasty (DLEK) and penetrating keratoplasty (PK) for endothelial dysfunction.DESIGN: A randomized clinical trial.METHODS: Thirteen eyes (12 patients) were randomized to DLEK with a 9 mm scleral incision, and 15 eyes (14 patients) were randomized to PK. The primary outcome was high contrast best spectacle-corrected visual acuity (BSCVA) at 12 months after surgery; intraocular forward light scatter and corneal backscatter were measured at one, three, six, and 12 months after surgery.RESULTS: BSCVA at 12 months was 0.34 +/- 0.16 logMAR (logarithm of the minimum angle of resolution) for DLEK and 0.25 +/- 0.21 logMAR for PK (P = .23; minimum detectable difference at 12 months was 0.23 logMAR). The change in postoperative forward light scatter after DLEK correlated with the change in BSCVA (r = -0.66; P