Trichomonas vaginalis infection and risk of advanced prostate cancer
Trichomonas vaginalis infection and risk of advanced prostate cancer
复制标题
DOI：
10.1002/pros.23153
复制
发表时间：
2016-05-15
期刊：
影响因子：
2.8
通讯作者：
Stanford, Janet L.
中科院分区：
文献类型：
--
作者：
Shui, Irene M.;Kolb, Suzanne;Stanford, Janet L.
BACKGROUNDThe epidemiologic evidence for an association of Trichomonas vaginalis (Tv) with overall prostate cancer is mixed, but some studies suggest Tv may increase risk of more aggressive disease. The aim of this study was to assess whether Tv serostatus is associated with advanced or fatal prostate cancer.METHODSA total of 146 men with advanced (metastatic or fatal) prostate cancer and 181 age-matched controls were selected from two prior population-based, case-control studies. Tv serostatus was determined with the same laboratory methods used in previous epidemiologic studies. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multivariable logistic regression to compare Tv serostatus in prostate cancer cases and controls adjusted for potential confounders.RESULTSThe seroprevalence of Tv in controls was 23%. Tv serostatus was not associated with an increased risk of metastatic or fatal prostate cancer (ORs
