The relationship between TEM8 and early diagnosis and prognosis of lung cancer
The relationship between TEM8 and early diagnosis and prognosis of lung cancer
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DOI：
10.23736/s0026-4806.20.06444-7
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发表时间：
2021-06-01
期刊：
影响因子：
4.7
通讯作者：
Liu, Shiyong
中科院分区：
文献类型：
--
作者：
Sun, Minghua;Li, Hua;Liu, Shiyong
背景：探讨TEM8在肺癌患者中的表达及其与临床病理、预后的关系，分析TEM8的诊断价值。方法：选取2013年3月至2016年2月在扎兰屯中盟医院和锦州医科大学第一附属医院诊断治疗的肺癌患者204例作为研究组，203例为对照组。采用qRT-PCR技术检测TEM8的表达。结合临床资料，分析TEM8对肺癌的诊断价值及与TEM8临床特征的相关性。比较TEM8低表达和高表达患者的3年生存曲线。结果：研究组的表达明显高于对照组(P
BACKGROUND: To explore the TEM8 expression in patients with lung cancer and its relationship with clinical pathology and prognosis, and to analyze the diagnostic value of TEM8.METHODS: A total of 204 patients with lung cancer diagnosed and treated in Zhongmeng Hospital Zhalantun and the First Affiliated Hospital of Jinzhou Medical University from March 2013 to February 2016 were enrolled in the study croup, and 203 healthy subjects in the control group. qRT-PCR technique was applied to detect the TEM8 expression. Combined with clinical information, the diagnostic value of TEM8 for lung cancer and the correlation of clinical characteristics of TEM8 were analyzed. The 3-year survival curves of patients with low and high TEM8 expressions were compared.RESULTS: The expression in the study group was significantly higher than that in the control group (P