A coccidioidomycosis outbreak following the Northridge, Calif, earthquake
A coccidioidomycosis outbreak following the Northridge, Calif, earthquake
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DOI：
10.1001/jama.277.11.904
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发表时间：
1997-03-19
影响因子：
120.7
通讯作者：
Werner, SB
中科院分区：
文献类型：
--
作者：
Schneider, E;Hajjeh, RA;Werner, SB
客观。-描述1994年1月地震后文图拉县的球孢子菌病爆发，以加利福尼亚州北岭为中心，并确定增加获得急性球孢子菌病感染风险的因素。流行病学调查、人群皮试调查和病例对照研究。加利福尼亚州文图拉县结果在文图拉县，1994年1月24日至3月15日期间，确定了203例与球孢子菌病爆发相关的病例，包括3例死亡（发病率[AR]，每10万人口30例）。大多数病例（56%）和最高AR（每10万人口114例）发生在西米谷镇，该社区位于一个山脉底部，经历了与地震相关的多次山体滑坡。病例发病高峰在地震后2周。40岁及以上人群的AR是年轻人群的2.8倍（相对危险度，2.8; 95%可信区间[CI]，2.1-3.7; P
Objective.-To describe a coccidioidomycosis outbreak in Ventura County following the January 1994 earthquake, centered in Northridge, Calif, and to identify factors that increased the risk for acquiring acute coccidioidomycosis infection.Design.-Epidemic investigation, population-based skin test survey, and case-control study.Setting.-Ventura County, California.Results.-In Ventura County, between January 24 and March 15, 1994, 203 outbreak-associated coccidioidomycosis cases, including 3 fatalities, were identified (attack rate [AR], 30 cases per 100 000 population). The majority of cases (56%) and the highest AR (114 per 100 000 population) occurred in the town of Simi Valley, a community located at the base of a mountain range that experienced numerous landslides associated with the earthquake. Disease onset for cases peaked 2 weeks after the earthquake. The AR was 2.8 times greater for persons 40 years of age and older than for younger persons (relative risk, 2.8; 95% confidence interval [CI], 2.1-3.7; P