Enantioselective Organocatalytic Three-Component Petasis Reaction among Salicylaldehydes, Amines, and Organoboronic Acids
Enantioselective Organocatalytic Three-Component Petasis Reaction among Salicylaldehydes, Amines, and Organoboronic Acids
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DOI：
10.1021/ol203109a
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发表时间：
2012-02-17
期刊：
影响因子：
5.2
通讯作者：
Yuan, Wei-Cheng
中科院分区：
文献类型：
--
作者：
Han, Wen-Yong;Wu, Zhi-Jun;Yuan, Wei-Cheng
The catalytic enantioselective three-component Petasis reaction among salicylaldehydes, amines, and organoboronic acids with a newly designed thiourea-binol catalyst is presented. A broad range of alkylaminophenols can be obtained in good yield (up to 92%) and good to high enantioselectivity (up to 95% ee). A possible reaction pathway for this catalytic enantioselective Petasis reaction is tentatively proposed.
