Possible association between Behçet's syndrome and chronic hepatitis C virus infection.

Possible association between Behçet's syndrome and chronic hepatitis C virus infection.
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白塞氏综合征与慢性丙型肝炎病毒感染之间可能存在关联。

DOI:
10.1056/nejm199502093320616
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发表时间:
1995
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
Giuliano Ramadori
Giuliano Ramadori
中科院分区:
--
文献类型:
--
作者:
Hans Münke;Fritz Stöckmann;Giuliano Ramadori

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致编辑:已知许多免疫系统疾病与慢性丙型肝炎病毒(HCV)感染有关。1我们报告了慢性HCV感染与白塞氏综合征之间的可能联系。1985年,一名先前健康的妇女因给予凝血因子而感染HCV。发生急性肝炎,随后转氨酶水平持续中度升高。1990年,患者出现口腔和生殖器溃疡、上半身脓疱、多关节炎、结膜炎和发热。白塞氏综合征被诊断,治疗与强的松减轻症状。然后将硫唑嘌呤添加到治疗方案中。. . .
To the Editor: A number of immunologic disorders are known to be associated with chronic hepatitis C virus (HCV) infection.1 We report a possible association between chronic HCV infection and Behcet's syndrome. A previously healthy woman was infected with HCV by the administration of coagulation factors in 1985. Acute hepatitis developed, followed by persistent moderate elevations of aminotransferase levels. In 1990 the patient presented with oral and genital ulcerations, pustules on the upper part of the body, polyarthritis, conjunctivitis, and fever. Behcet's syndrome was diagnosed, and therapy with prednisone reduced the symptoms. Azathioprine was then added to the treatment regimen. . . .