Ileal Crohn's disease: MRI with endoscopic correlation
Ileal Crohn's disease: MRI with endoscopic correlation
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DOI：
10.1016/j.ejrad.2010.05.042
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发表时间：
2011-11-01
影响因子：
3.3
通讯作者：
Ollero, Virginia
中科院分区：
文献类型：
--
作者：
Gallego, Jose C.;Echarri, Ana I.;Ollero, Virginia
目的：目的：以回肠镜检查为参考标准，评价磁共振小肠造影对克罗恩病（CD）活动性分期的价值。所有患者均行MR小肠造影和回肠镜检查。MRI活动通过专门的评分以及对成像结果的分析来测量，并与通过回肠镜检查获得的SES-CD评分进行比较。检查使用1.0 T扫描仪进行。结果：MRI评分区分活动性和非活动性疾病的ROC曲线下面积为0.941。与标准参考SES-CD评分的总体相关性为中度至强（斯皮尔曼r = 0.62 p < 0.001）。在将回肠CD患者分期为非活动性、轻度或中度至重度方面，两种方法之间的一致性良好（科恩kappa = 0.60）。三组MRI活动性评分的平均值差异具有统计学意义（p < 0.01）。结论：MRI评分是回肠CD活动性的可靠预测因子，可与内镜相媲美地对患者进行分期。1.0 T扫描对于回肠克罗恩病的放射学评价是有效的。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Purpose: To evaluate activity staging of Crohn's disease (CD) measured with MR-enterography using ileoscopy as reference standard.Materials and methods: A prospective study was made of 61 patients with CD. All patients underwent MR-enterography and ileoscopy. MRI activity was measured by means of an ad hoc developed score, as well as by analysis of the imaging findings, and was compared with the SES-CD score obtained via ileoscopy. Examinations were performed using a 1.0 T scanner.Results: MRI score discriminates between active and inactive disease with an area under the ROC curve of 0.941. Overall correlation with the standard reference SES-CD score was moderate to strong (Spearman's r = 0.62 p < 0.001).Agreement between both methods in staging patients with ileal CD as inactive, mild or moderate to severe was good (Cohen's kappa = 0.60). Differences in means of the MRI activity scores of the three groups showed statistical significance (p < 0.01).Conclusions: The MRI score is a reliable predictor of activity in ileal CD and can stage patients in a way comparable to endoscopy. 1.0 T scans are valid for performing radiological evaluation of ileal Crohn's disease. (C) 2010 Elsevier Ireland Ltd. All rights reserved.