Psychosocial Late Effects in Pediatric Cancer Survivors: A Report From the Children's Oncology Group.
Psychosocial Late Effects in Pediatric Cancer Survivors: A Report From the Children's Oncology Group.
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DOI：
10.1002/pbc.25773
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发表时间：
2016-02
影响因子：
3.2
通讯作者：
Klosky JL
中科院分区：
文献类型：
--
作者：
Bitsko MJ;Cohen D;Dillon R;Harvey J;Krull K;Klosky JL
这篇综述是为了更新儿童肿瘤学会(COG)长期随访指南(COG-LTFU指南；版本4.0)关于筛查儿童癌症的心理社会后遗症。由COG晚期效应专家组成的多学科团队对2009年8月至2011年1月期间发表的涉及儿童癌症长期幸存者(n=35)的心理社会晚期效应的文章进行了审查。这一时期的大多数研究表明，幸存者在长期生存中经历的心理社会问题很少。然而，一个关键的亚组面临着治疗后继发的心理社会后遗症的风险增加。这项综述的重点发现包括自杀意念(SI)发生率的增加，以及健康信念作为SI、焦虑和全球痛苦的有力预测因素。幸存者的健康信念与他们对身体限制、整体迟发效应和癌症相关疼痛的看法有关。虽然许多生存研究继续明确焦虑和创伤后应激症状(PTSS)/精神障碍(PTSD)的风险因素，但其他结果(如发展、人际关系和家庭因素)似乎正在变得重要起来。尽管大多数儿童癌症幸存者没有经历过心理社会问题，但有一小部分人会经历。最近的研究结果已被纳入新的COG-LTFU指南，该指南将有助于有针对性地评估和治疗幸存者的心理社会健康。
This review was conducted to update the Children’s Oncology Group (COG) Long-Term Follow-Up Guidelines (COG-LTFU Guidelines; version 4.0) regarding screening for psychosocial late effects of pediatric cancer. Articles published between August 2009 and January 2011 that addressed psychosocial late effects of long-term survivors of pediatric cancer (n = 35) were reviewed by a multidisciplinary team of COG late effect experts. The majority of studies in this time period indicate that survivors experience few psychosocial problems in long-term survivorship. A critical subset, however, are at increased risk for psychosocial late effects secondary to treatment. Highlighted findings from this review include increased rates of suicidal ideation (SI), and health beliefs as robust predictors of SI, anxiety, and global distress. Survivors’ health beliefs were associated with their perceptions of physical limitations, overall late effects, and cancer-related pain. While many survivorship studies continue to specify risk factors for anxiety and post-traumatic stress symptoms (PTSS)/disorder (PTSD), others outcomes (e.g. developmental, interpersonal, and familial factors) appear to be emerging in importance. Although the majority of childhood cancer survivors do not experience psychosocial problems, a subset will. The recent research findings have been included in the new COG-LTFU guidelines that will assist in the targeted assessment and treatment of survivors’ psychosocial health.