Protective barrier effect of the posterior lens capsule in exogenous bacterial endophthalmitis--an experimental primate study.
Protective barrier effect of the posterior lens capsule in exogenous bacterial endophthalmitis--an experimental primate study.
复制标题
晶状体后囊在外源性细菌性眼内炎中的保护屏障作用——一项灵长类动物实验研究。
DOI：
--
复制
发表时间：
1984
影响因子：
4.4
通讯作者：
F. O'Donnell
中科院分区：
文献类型：
--
作者：
T. L. Beyer;G. Vogler;D. Sharma;F. O'Donnell
五只恒河猴的十只眼睛接受了囊外晶状体摘除术。每只猴子的右眼都保留完整的后囊膜。每只猴子的左眼均进行了广泛的初级囊切除术和最小的前玻璃体切除术。为了排除手术污染，我们等了2到3周后才用细菌挑战眼睛。前房注射等量金黄色葡萄球菌后 72 小时，从前房和玻璃体获得诊断培养物，并将其与临床结果相关联。注射 10,000 个金黄色葡萄球菌，在接受后囊切除术的眼睛中产生培养阳性眼内炎，但在后囊完整的另一眼中却未能产生眼内炎。这表明在后囊完整的眼睛中存在对细菌性眼内炎发展的显着屏障作用。
Ten eyes of five Rhesus monkeys underwent extracapsular lens extraction. The right eye of each monkey was allowed to retain an intact posterior capsule. The left eye of each monkey had a wide primary capsulectomy with minimal anterior vitrectomy. In order to exclude operative contamination, we waited 2 to 3 weeks later to challenge the eyes with bacteria. Seventy-two hours after anterior chamber injection of equal numbers of Staphylococcus aureus, diagnostic cultures were obtained from the anterior chamber and vitreous and correlated with the clinical findings. Injection of 10,000 S. aureus produced culture-positive endophthalmitis in eyes that had undergone posterior capsulectomy, but it failed to produce endophthalmitis in fellow eyes with intact posterior capsules. This suggest that a significant barrier effect against the development of bacterial endophthalmitis exists in the eyes with intact posterior capsules.
磷酸倍他米松、磷酸地塞米松和吲哚美辛对牛血清白蛋白诱导的兔眼部炎症的抗炎作用。
影响因子：
2
作者：
Kulkarni,PS;Bhattacherjee,P;Eakins,KE;Srinivasan,BD
通讯作者：
Srinivasan,BD