Longitudinal study of changes in hip bone mineral density in Caucasian and African-American women
Longitudinal study of changes in hip bone mineral density in Caucasian and African-American women
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DOI：
10.1111/j.1532-5415.2005.53101.x
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发表时间：
2005-02-01
影响因子：
6.3
通讯作者：
Ensrud, KE
中科院分区：
文献类型：
--
作者：
Cauley, JA;Lui, LY;Ensrud, KE
目的：确定高加索和非洲裔美国妇女髋部骨矿物质密度（BMD）的变化是否不同。设计：髋部BMD变化的纵向研究。地点：4个美国临床中心。参与者：607名高加索人。（平均年龄73岁）和482名非洲裔美国人（平均年龄75岁）妇女参加骨质疏松性骨折的研究。测量全髋关节和股骨颈BMD平均间隔3.5年（白人）和2.0年（非洲裔美国人）。结果：白种人全髋（-0.574%/y vs -0.334%/y）和股骨颈（-0.515%/y vs-0.203%/y）BMD的多变量校正年百分比变化大于非裔美国妇女（均为P
OBJECTIVES: To determine whether changes in hip bone mineral density (BMD) differ in Caucasian and African American women.DESIGN: Longitudinal study of changes in hip BMD.SETTING: Four U.S. clinical centers.PARTICIPANTS: Six thousand seven Caucasian (mean age 73) and 482 African-American (mean age 75) women enrolled in the Study of Osteoporotic Fractures.MEASUREMENTS: Total hip and femoral neck BMD were measured an average of 3.5 years apart (Caucasian) and 2.0 years apart (African American). Annual absolute and percentage changes in BMD and bone mineral apparent density (BMAD) were calculated.RESULTS: The multivariate adjusted annual percentage change in BMD was greater in Caucasian than African-American women at the total hip (-0.574%/y vs -0.334%/y) and femoral neck (-0.515%/y vs -0.203%/y) (both, P