Constructing Experimental Designs for Discrete-Choice Experiments: Report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force
Constructing Experimental Designs for Discrete-Choice Experiments: Report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force
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DOI：
10.1016/j.jval.2012.08.2223
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发表时间：
2013-01-01
期刊：
影响因子：
4.5
通讯作者：
Bridges, John F. P.
中科院分区：
文献类型：
--
作者：
Johnson, F. Reed;Lancsar, Emily;Bridges, John F. P.
状态偏好法是一类研究患者和其他利益相关者偏好的评估技术。虽然这些方法涉及多种技术，但联合分析方法，特别是离散选择实验（dce）近年来已成为医疗保健中最常用的方法。实验设计是这些方法发展的一个重要阶段，但由于缺乏对现有技术和软件的了解，在标准上建立共识受到阻碍。本报告以先前的ISPOR联合分析工作组报告为基础：联合分析在健康中的应用核对表：ISPOR联合分析工作组良好研究实践报告。本报告旨在帮助研究人员具体评估实验设计的替代方法，这是成功的dce的一个困难和重要因素。虽然本报告不支持任何具体的方法，但它确实为选择适合特定研究的方法提供了指导。特别是，它概述了实验设计对于成功实施DCE方法在卫生保健研究中的作用，并为研究人员提供了基于研究目标和研究人员为研究选择的统计模型构建实验设计的介绍。该报告概述了确定选择模型偏好参数的设计的理论要求，并总结和比较了构建实验设计的一些可用方法。工作队领导小组通过两个月一次的电话会议和在美国和欧洲举行的ISPOR会议亲自举行会议。在此过程中，咨询了一个国际实验设计专家小组，讨论现有的实验设计方法，并审查工作组的报告草案。此外，ISPOR成员在审查过程中提交了书面意见，并在巴尔的摩（2011年）和华盛顿特区（2012年）举行的ISPOR第16届和第17届年度国际会议的两次论坛演讲中提交了口头意见，为制定共识报告做出了贡献。
Stated-preference methods are a class of evaluation techniques for studying the preferences of patients and other stakeholders. While these methods span a variety of techniques, conjoint-analysis methods and particularly discrete-choice experiments (DCEs) have become the most frequently applied approach in health care in recent years. Experimental design is an important stage in the development of such methods, but establishing a consensus on standards is hampered by lack of understanding of available techniques and software. This report builds on the previous ISPOR Conjoint Analysis Task Force Report: Conjoint Analysis Applications in Health A Checklist: A Report of the ISPOR Good Research Practices for Conjoint Analysis Task Force. This report aims to assist researchers specifically in evaluating alternative approaches to experimental design, a difficult and important element of successful DCEs. While this report does not endorse any specific approach, it does provide a guide for choosing an approach that is appropriate for a particular study. In particular, it provides an overview of the role of experimental designs for the successful implementation of the DCE approach in health care studies, and it provides researchers with an introduction to constructing experimental designs on the basis of study objectives and the statistical model researchers have selected for the study. The report outlines the theoretical requirements for designs that identify choice-model preference parameters and summarizes and compares a number of available approaches for constructing experimental designs. The task-force leadership group met via bimonthly teleconferences and in person at ISPOR meetings in the United States and Europe. An international group of experimental-design experts was consulted during this process to discuss existing approaches for experimental design and to review the task force's draft reports. In addition, ISPOR members contributed to developing a consensus report by submitting written comments during the review process and oral comments during two forum presentations at the ISPOR 16th and 17th Annual International Meetings held in Baltimore (2011) and Washington, DC (2012).