A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping
A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping
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DOI：
10.1007/s00062-015-0450-7
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发表时间：
2015-10-01
影响因子：
2.8
通讯作者：
Jansen, O.
中科院分区：
文献类型：
--
作者：
Lindner, T.;Helle, M.;Jansen, O.
动脉自旋标记（ASL）是一种新兴的方法，用于评估各种脑部疾病的灌注。在ASL中，动脉血液水自旋的磁化在流入感兴趣的组织之前以完全非侵入性的方式进行操纵。这允许绝对定量的脑血流，从而提出了一种替代的对比度增强的方法，基于计算机断层扫描或磁共振成像。此外，其潜在的应用程序的流动领域映射可以提供额外的信息的个人配置的脑内血流。本文简要介绍了ASL的基本方法及其成像方法。此外，ASL在各种脑血管疾病的利用提供了（领土）ASL在临床常规的潜在应用的例子。
Arterial spin labeling (ASL) is an emerging method for the assessment of perfusion in various diseases of the brain. In ASL, the magnetization of arterial blood water spins is manipulated in a complete non-invasive way before flowing into the tissue of interest. This allows absolute quantification of cerebral blood flow, thereby, presenting an alternative to contrast-enhanced methods based on computed tomography or magnetic resonance imaging. Furthermore, its potential application for flow territory mapping can provide additional information of the individual configuration of intracerebral blood flow. This article gives a brief overview of the basic ASL methodology and its approaches to image individual perfusion territories. Additionally, the utilization of ASL in a variety of cerebrovascular diseases is presented to provide examples of potential applications of (territorial) ASL in clinical routine.