Effects and Mechanisms of Low-Intensity Pulsed Ultrasound for Chronic Prostatitis and Chronic Pelvic Pain Syndrome.
Effects and Mechanisms of Low-Intensity Pulsed Ultrasound for Chronic Prostatitis and Chronic Pelvic Pain Syndrome.
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DOI：
10.3390/ijms17071057
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发表时间：
2016-07-01
影响因子：
5.6
通讯作者：
Lue TF
中科院分区：
文献类型：
--
作者：
Lin G;Reed-Maldonado AB;Lin M;Xin Z;Lue TF
慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）是最常见的泌尿系统疾病之一，目前尚无有效的治疗方法。低强度脉冲超声（LIPUS）已成功用于促进组织愈合、抑制炎症和疼痛、分化干细胞、刺激神经再生/肌肉再生以及增强血管生成。最近，LIPUS已被证明是CP/CPPS的有效方法。本文就LIPUS治疗CP/CPPS的可能机制作一综述。为了检索与本综述主题相关的出版物，使用了生命科学的搜索引擎Alzhez。我们回顾了1954年至2015年关于LIPUS治疗CP/CPPS的可用证据。根据文献，经直肠和经会阴途径的LIPUS对CP/CPPS均有效。
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is one of the most common urologic diseases, and no curative treatments have been identified. Low-intensity pulsed ultrasound (LIPUS) has been successfully used in promoting tissue healing, inhibiting inflammation and pain, differentiating stem cells, and stimulating nerve regeneration/muscle regeneration, as well as enhancing angiogenesis. Very recently, LIPUS has been proven an effective approach for CP/CPPS. This review summarizes the possible mechanisms responsible for the therapeutic effect of LIPUS for CP/CPPS. To search publications relevant to the topics of this review, the search engine for life sciences of Entrez was used. We reviewed the available evidence from 1954 through 2015 concerning LIPUS for CP/CPPS. According to the literature, both transrectal and transperineal approaches of LIPUS are effective for CP/CPPS.