Outcome of preterm infants born to overweight and obese mothers
Outcome of preterm infants born to overweight and obese mothers
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DOI：
10.1080/14767058.2016.1177016
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发表时间：
2017-01-01
影响因子：
1.8
通讯作者：
Leibovitch, L.
中科院分区：
文献类型：
--
作者：
Danieli-Gruber, S.;Maayan-Metzger, A.;Leibovitch, L.
目的：评估超重和肥胖母亲所生早产儿的围产期发病率和死亡率，与孕前体重指数 (BMI) 正常的母亲所生早产儿相比。方法：回顾性记录 110 名超重 (n = 68) 和肥胖 (n = 42) 母亲在孕龄 (GA) 28-34 周所生早产儿的医学图表，以及 110 个与 GA 和出生体重相匹配的对照。所有婴儿均于 2007 年至 2014 年间在 Sheba 医疗中心出生。记录了有关母亲孕前体重和身高的数据，以及孕产妇和新生儿并发症和喂养方法。结果：肥胖母亲有更多的妊娠高血压综合征（52.4% vs 21.4%，p = 0.006）和剖腹产（81% vs 52.4%，p = 0.018）。超重母亲患妊娠期糖尿病的比例更高（20.6% vs 2.9%，p = 0.001）。研究组和对照组的所有新生儿结局参数均相似。在整个住院期间，各组之间在阿普加评分、呼吸窘迫和支持、低血压、心脏表现、脑部病变、感染、喂养类型和总住院天数方面没有记录到差异。结论：尽管肥胖和超重女性的产妇并发症较多，但这些女性所生的早产儿似乎并没有增加新生儿并发症的风险。
Objectives: To evaluate perinatal morbidity and mortality among preterm neonates who were born to overweight and obese mothers compared to preterm neonates who were born to mothers with normal pre-pregnancy body mass index (BMI).Methods: Retrospective recordings of medical charts of 110 preterm infants born to overweight (n = 68) and obese (n = 42) mothers at gestational age (GA) 28-34 weeks, as well as 110 controls matched for GA and birth weight. All infants were born at the Sheba Medical Center between 2007 and 2014. Data regarding maternal pre-pregnancy weight and height were recorded, as well as maternal and neonatal complications and feeding methods.Results: Obese mothers had more pregnancy-induced hypertension (52.4% versus 21.4%, p = 0.006) and caesarean section deliveries (81% versus 52.4%, p = 0.018). Overweight mothers had more gestational diabetes (20.6% versus 2.9%, p = 0.001). The study and control groups were similar on all neonatal outcome parameters. No differences between the groups were recorded throughout hospitalization with respect to Apgar score, respiratory distress and support, hypotension, cardiac manifestations, brain pathologies, infection, feeding type and total hospitalization days.Conclusions: Although the maternal complications are greater among obese and overweight women, it seems that preterm infants born to these women are not at increased risk for neonatal complications.