Parallel reconstruction in accelerated multivoxel MR spectroscopy
Parallel reconstruction in accelerated multivoxel MR spectroscopy
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DOI：
10.1002/mrm.25718
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发表时间：
2015-09-01
影响因子：
3.3
通讯作者：
Barker, P. B.
中科院分区：
文献类型：
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作者：
Boer, V. O.;Klomp, D. W. J.;Barker, P. B.
目的利用灵敏度编码技术开发局部磁共振光谱（MRS）中多体素的同时采集，与传统的顺序单体素（SV）采集方法相比，减少了总扫描时间。方法采用双体积定位法，同时激发双脑体素。利用接收线圈灵敏度曲线展开数据。为了验证该方法，在3特斯拉(T)时测量左、右海马的MRS体素，在7特斯拉(T)时测量左、右运动皮质的MRS体素。将光谱与常规SV采集进行比较。我们还记录了一个低级别少突胶质细胞瘤患者在7T时的病变和对侧半球的光谱。结果可以同时在两个体素中产生信号，并将不同位置的信号分离，其光谱结果与传统的单体素方法几乎相同。该方法会导致化学位移伪影增加，这可以通过先进的脉冲设计来改善，并且由于展开g因子而导致噪声增加，在3T时比7T时更大。结论利用调制的切片选择脉冲和接收线圈灵敏度曲线来展开所得到的信号，可以实现MRS体素的同步采集。中华医学杂志，2015,34(4):591 - 596。(c) 2015 Wiley期刊公司
PurposeTo develop the simultaneous acquisition of multiple voxels in localized MR spectroscopy (MRS) using sensitivity encoding, allowing reduced total scan time compared to conventional sequential single voxel (SV) acquisition methods.MethodsDual volume localization was used to simultaneously excite voxels in both hemispheres. Receiver coil sensitivity profiles were used to unfold the data. To demonstrate the method, MRS voxels in the left and right hippocampus were measured at 3 tesla (T) and the left and right motor cortices at 7T. Spectra were compared to conventional SV acquisitions. Spectra were also recorded from the lesion and contralateral hemisphere of a patient with a low-grade oligodendroglioma at 7T.ResultsIt was possible to generate signal in two voxels simultaneously and separate the signal originating from the different locations, with spectral results almost identical to those observed using conventional single voxel methods. The method results in an increased chemical shift displacement artifact, which might be improved by advanced pulse designs, and a noise increase due to the unfolding g-factor, which was larger at 3T than 7T.ConclusionThe simultaneous acquisition of voxels for MRS is possible by using modulated slice-selective pulses and receive coil sensitivity profiles to unfold the resulting signals. Magn Reson Med 74:599-606, 2015. (c) 2015 Wiley Periodicals, Inc.