Significant invasion depth of early oral tongue cancer originated from the lateral border to predict regional metastases and prognosis
Significant invasion depth of early oral tongue cancer originated from the lateral border to predict regional metastases and prognosis
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DOI：
10.1016/j.ijom.2009.01.004
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发表时间：
2009-06-01
影响因子：
2.4
通讯作者：
Kim, S. -H
中科院分区：
文献类型：
--
作者：
Jung, J.;Cho, N. H.;Kim, S. -H
在口腔舌癌中，肿瘤深度对颈淋巴转移是至关重要的。没有标准的方法来预测肿瘤的侵袭或决定谁应该接受选择性颈淋巴清扫术。在这项研究中，将计算的MRI侵袭深度与组织病理学(HP)侵袭深度进行比较，以找出相关性，并确定预测隐匿性颈淋巴结转移的侵袭深度的临界值。对50例临床诊断为舌侧缘癌T1或T2的患者进行了MRI检查，并进行了手术切除。比较MRI和Hp的侵袭深度，并确定临界值。判断有无淋巴结转移的特异度和敏感度总和最高的侵袭深度分别为8.5 mm HP、10.5 mm T1WI和11.5 mm T2加权轴位。MRI T2加权像的侵犯深度与HP深度的相关系数为0.851，准确率为84%，与T1加权增强轴位图像相比具有更高的相关性。幽门螺杆菌深度与生存率显著相关。利用MRI测量口腔舌癌的侵袭深度是确定早期口腔舌癌手术方案的先决条件。
In oral tongue cancer, tumor depth is crucial for cervical lymph node metastasis. There is no standardized method to predict tumor invasion or deciding Who should undergo selective neck dissection. In this study, calculated MRI invasion depth was compared with histopathologic (HP) invasion depth to find a correlation, and determine a cutoff value of invasion depth that predicts occult neck node metastasis. 50 patients, diagnosed with T1 or T2 oral tongue cancer originating front the lateral border of the tongue, underwent MRI screening and received surgical excision as primary treatment. MRI and HP invasion depths were compared and the Cutoff value determined. The invasion depth to determine the presence of nodal metastasis where summation of specificity and sensitivity was greatest was 8.5 mm HP, 10.5 mm in T1 weighted enhanced axial image, and 11.5 mm in T2 weighted MRI axial image. The relation coefficient of T2 weighted MRI invasion depth and HP depth was 0.851, and accuracy 84%, all of which showed higher correlation compared with T1 weighted enhanced axial image. HP depth was significantly correlated With survival rate. The measurement of invasion depth using MRI is a prerequisite for determining a surgical plan in early oral tongue cancer.