Neural basis of individual differences in impulsivity: Contributions of corticolimbic circuits for behavioral arousal and control
Neural basis of individual differences in impulsivity: Contributions of corticolimbic circuits for behavioral arousal and control
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DOI：
10.1037/1528-3542.6.2.239
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发表时间：
2006-05-01
期刊：
影响因子：
4.2
通讯作者：
Hariri, Ahmad R.
中科院分区：
文献类型：
--
作者：
Brown, Sarah M.;Manuck, Stephen B.;Hariri, Ahmad R.
本研究的目的是通过健康成年受试者的功能性MRI杏仁核反应性和前额叶抑制控制范式，分析行为唤醒和抑制控制的神经相关性，因为它们与个体差异有关。冲动性与双侧腹侧杏仁核的活动呈正相关。海马旁回扣带回背侧前回（BA32）。和双侧Cuadate。相反，冲动性与杏仁核和腹侧前额叶皮层的活动呈负相关（BA 47）。一起这些发现表明，性格冲动受到皮质边缘行为唤醒和控制回路的功能相互作用的影响。
The objective of the current Study Was to analyze the neural correlates of behavioral arousal and inhibitory control as they relate to individual differences ill via well-established functional MRI amygdala reactivity and prefrontal inhibitory control paradigms in healthy adult subjects. Impulsivity correlated positively with activity of the bilateral ventral amygdala. parahippocampal gyrus. dorsal anterior cingulate gyrus (BA 32). and bilateral Cuadate. Conversely, impulsivity correlated negatively with activity of the dorsal amygdala and ventral prefrontal cortex (BA 47). Together. these findings Suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits.