Evidence-Supported Interventions for Reducing Secondary Stroke Risk in Sub-Saharan Africa: A Systematic Review.
Evidence-Supported Interventions for Reducing Secondary Stroke Risk in Sub-Saharan Africa: A Systematic Review.
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DOI：
10.2147/ndt.s428627
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发表时间：
2023
影响因子：
3.2
通讯作者：
Kaddumukasa, Mark
中科院分区：
文献类型：
--
作者：
Kaddumukasa, Martin;Edwards, Alyssa M.;Najjuma, Josephine Nambi;Mbalinda, Scovia Nalugo;Nakibuuka, Jane;Burant, Christopher J.;Moore, Shirley M.;Blixen, Carol;Katabira, Elly;Sajatovic, Martha;Kaddumukasa, Mark
这项研究旨在对旨在降低非洲继发性中风风险的循证干预措施进行系统的文献回顾。这项综述分析了在撒哈拉以南非洲地区进行的纵向干预研究，重点是既往中风的成年参与者。它涵盖了来自著名数据库的出版物和同行评议的论文，包括PubMed、Ovid、Cochrane和Web of Science。纳入了三项随机临床试验(RCT)研究，样本大小从16到400人不等，平均年龄在50到66岁之间，其中64.5%是男性参与者。所有研究都采用了多学科团队干预，加强了患者随访，涉及护理人员、护士教育人员、医生和社会工作者。干预措施包括全面的患者教育、跟踪服药依从性和强制实施健康的生活方式行为(定期锻炼、定期测量血压和改变饮食)。我们发现，3个治疗组中有2个随着时间的推移收缩压降低，所有治疗组的服药依从性都有所改善，1个治疗组的胆固醇水平有所下降。包括多学科团队和全面的患者教育在内的循证干预被发现在降低非洲的继发性中风风险方面显示出有希望的结果，导致大多数治疗组的医疗依从性显著提高，收缩压降低。然而，需要更多的研究来证实这些干预措施对胆固醇水平的影响，并确定它们在预防非洲社区中风方面的持久优势。
The study set out to perform a systematic literature review of evidence-based interventions that target the reduction of secondary stroke risk in Africa. The review analyzed longitudinal intervention studies conducted in Sub-Saharan Africa, focusing on adult participants who had suffered a prior stroke. It encompassed publications and peer-reviewed papers sourced from reputable databases, including PubMed, Ovid, Cochrane, and Web of Science. Three randomized clinical trial (RCT) studies were included with sample sizes ranging from 16 to 400 participants, mean age ranged between 50 and 66 years, with 64.5% male participants. All studies applied multidisciplinary team interventions of enhanced patient follow-up involving care givers, nurse educators, physicians, and social workers. Interventions ranged from comprehensive patient education, tracking of medication adherence and enforcing healthy lifestyle behaviors (regular exercise, regular BP checks, and dietary changes). We found a decrease in Systolic Blood Pressure over time in 2 of 3 treatment groups, an improvement in medical adherence in all treatment groups, and a decrease in cholesterol levels in 1 treatment group. Evidence-based interventions involving multidisciplinary teams and comprehensive patient education were found to demonstrate promising results in reducing secondary stroke risk in Africa, leading to significant improvements in medical adherence and reductions in systolic blood pressure in the majority of treatment groups. However, more research is required to confirm the influence of these interventions on cholesterol levels and to establish their lasting advantages in preventing strokes among African communities.
影响因子：
3.9
作者：
Cao C;Jain N;Lu E;Sajatovic M;Still CH
通讯作者：
Still CH