Production of 47Sc, 67Cu, 68Ga, 105Rh, 177Lu, and 188Re using electron linear accelerator
Production of 47Sc, 67Cu, 68Ga, 105Rh, 177Lu, and 188Re using electron linear accelerator
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DOI：
10.1007/s10967-019-06904-z
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发表时间：
2019-11-01
影响因子：
1.6
通讯作者：
Ohtsuki, Tsutomu
中科院分区：
文献类型：
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作者：
Inagaki, Makoto;Sekimoto, Shun;Ohtsuki, Tsutomu
本研究利用电子直线加速器产生核医学中使用的放射性同位素（Sc-47、Cu-67、Ga-68、Rh-105、Lu-177和Re-188）。研究了中子辐照作为生产Rh-105和Lu-177的替代方法，并将结果与电子直线加速器获得的结果进行了比较。除Lu-177外，所有放射性同位素均由电子直线加速器有效产生。因此，电子直线加速器被证明显示出在医院等消费场所按需生产医用放射性同位素所需的性能。
Radioisotopes used in nuclear medicine (Sc-47, Cu-67, Ga-68, Rh-105, Lu-177, and Re-188) were produced by an electron linear accelerator in this study. Neutron irradiation was investigated as an alternative method for producing Rh-105 and Lu-177, and the results were compared with those obtained with the electron linear accelerator. All the radioisotopes except for Lu-177 were produced efficiently by the electron linear accelerator. Electron linear accelerators were thus demonstrated to show the desired performance for the on-demand production of medical radioisotopes at consuming places such as hospitals.