Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.

Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
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肯尼亚农村艾滋病毒感染的早期婴儿诊断的动力和约束。

DOI:
10.1007/s10461-010-9877-7
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发表时间:
2012-01
期刊:
影响因子:
4.4
通讯作者:
Berkley, James A.
Berkley, James A.
中科院分区:
医学2区
文献类型:
--
作者:
Hassan, Amin S.;Sakwa, Erick M.;Nabwera, Helen M.;Taegtmeyer, Miriam M.;Kimutai, Robert M.;Sanders, Eduard J.;Awuondo, Ken K.;Mutinda, Maureen N.;Molyneux, Catherine S.;Berkley, James A.

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队列设计被用来确定213名有资格进行艾滋病毒早期婴儿诊断(EID)的HIV暴露婴儿的吸收和退出。为了探索服务提供者和照顾者对开斋节过程的知识、态度和看法,我们进行了观察和深入访谈。145名婴儿(68%)在2个月大后登记。139例(65%)在随访至18个月前退出。60人(43%)在入学后2个月内辍学。与婴儿辍学相关的母亲因素是失去随访的母亲(48[68%]比8[20%],P=0.001)和较年轻的母亲年龄(27.2比30.1岁,P=0.033)。服务提供者和照顾者对EID的培训、知识和了解不足。贫穷和缺乏社会支持是获得开斋节服务的挑战。应在预防母婴传播服务中更紧密地协调EID,将其与常规的母婴保健活动结合起来,并更密切地监测其执行情况。
A cohort design was used to determine uptake and drop out of 213 HIV-exposed infants eligible for Early Infant Diagnosis (EID) of HIV. To explore service providers and care givers knowledge, attitudes and perceptions of the EID process, observations and in-depth interviews were conducted. 145 (68%) infants enrolled after 2 months of age. 139 (65%) dropped out before follow up to 18 months old. 60 (43%) drop outs occurred within 2 months of enrolment. Maternal factors associated with infant drop out were maternal loss to follow up (48 [68%] vs. 8 [20%], P < 0.001) and younger maternal age (27.2 vs. 30.1 years, P = 0.033). Service providers and caregivers had inadequate training, knowledge and understanding of EID. Poverty and lack of social support were challenges in accessing EID services. EID should be more closely aligned within PMTCT services, integrated with routine mother and child health (MCH) activities and its implementation more closely monitored.
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