Resection rates and postoperative mortality in 7,899 patients with lung cancer
Resection rates and postoperative mortality in 7,899 patients with lung cancer
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DOI：
10.1183/09031936.96.09010007
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发表时间：
1996-01-01
影响因子：
24.3
通讯作者：
Schutte, PR
中科院分区：
文献类型：
--
作者：
Damhuis, RAM;Schutte, PR
术后死亡是肺癌切除术的重要并发症，尤其是老年患者。为了支持一般情况下的决策，对当代结果和预后因素进行了评价。分析了1984年至1992年在鹿特丹癌症登记处所属医院诊断的7899例肺癌患者的计算机记录，以评估切除率和术后30天死亡率。在70岁及以上的患者中，切除率为14%，年轻患者为26%。术后死亡率为3.1%;男性3.6%，女性0.4%。多因素分析显示，年龄和手术范围是影响手术风险的主要因素。0-59岁、60-69岁和≥ 70岁患者的术后死亡率分别为1.4%、3.5%和4.0%，全肺切除术的手术风险为5.7%，双叶切除术的手术风险为4.4%，小切除术的手术风险为1.4%。在老年患者中进行子宫切除术的频率较低：年龄大于或等于70岁的患者中有27%的手术，而年轻患者中有37%的手术，年龄似乎与肺癌患者的治疗选择和术后死亡率有关，然而，即使在70岁以上的患者中，切除术也可以在可接受的风险下进行，这意味着实际年龄不应该自动决定治疗决定。
Postoperative death used to be an important complication of resections for lung cancer, especially in elderly patients. To support decision making in a general situation, contemporary results and prognostic factors were evaluated,The computer records of 7899 lung cancer patients, diagnosed from 1984 until 1992 in hospitals connected to the Rotterdam Cancer Registry, were analysed to evaluate resection rates and 30 day postoperative mortality.Resections were carried out in 20% of all patients, In patients 70 yrs of age and older, the resection rate was 14%, and in younger patients 26%. The postoperative mortality was 3.1%; 3.6% for males and 0.4% for females. According to multivariate analysis, age and extent of surgery were the major determinants of operative risk, For patients aged 0-59, 60-69 and greater than or equal to 70, postoperative mortality rates were 1.4, 3.5 and 4.0%, respectively, The operative risk was 5.7% after pneumonectomy, 4.4% after bilobectomy, and 1.4% after lesser resections. Pneumonectomies were performed less often in elderly patients: 27% of operations in patients greater than or equal to 70 yrs versus 37% of operations in younger patients,Age appears to be related to treatment choice and postoperative mortality in patients with lung cancer, However, even in patients over 70 yrs of age, resections can be performed at acceptable risk, implying that chronological age should not automatically determine treatment decisions.