Direct, one-step synthesis of condensed heterocycles: a palladium-catalyzed coupling approach.
Direct, one-step synthesis of condensed heterocycles: a palladium-catalyzed coupling approach.
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DOI：
10.1021/ol061404k
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发表时间：
2006-07
期刊：
影响因子：
5.2
通讯作者：
F. Jafarpour;M. Lautens
中科院分区：
文献类型：
--
作者：
F. Jafarpour;M. Lautens
[反应：见正文]报道了一种由双功能溴代烯酸酯或溴烷基吲哚和碘代芳烃在钯催化下一步合成稠合芳香杂环的方法。这种方法提供了一条从容易获得的原料中获得各种取代的多环芳烃和杂芳烃的有效途径。
[reaction: see text] A palladium-catalyzed one-step synthesis of fused aromatic heterocycles from bifunctional bromoenoates or bromoalkyl indoles and iodoarenes is reported. This method provides an efficient route to a wide variety of substituted polycyclic aromatic and heteroaromatic compounds from readily accessible starting materials.