Atherosclerosis of the ascending aorta is a predictor of renal dysfunction after cardiac operations
Atherosclerosis of the ascending aorta is a predictor of renal dysfunction after cardiac operations
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DOI：
10.1016/s0022-5223(99)70475-7
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发表时间：
1999-01-01
影响因子：
6
通讯作者：
Barzilai, B
中科院分区：
文献类型：
--
作者：
Dávila-Román, VG;Kouchoukos, NT;Barzilai, B
目的：心脏手术后发生的肾功能不全可归因于多种因素，但胸主动脉粥样硬化的重要性尚未得到评估。本研究的目的是确定术后肾功能不全的预测因素（较术前值增加50%或更多），并评估升主动脉粥样硬化作为该并发症预测因子的重要性，方法：978例连续患者，年龄50岁及以上，术前肾功能正常（血清肌酐水平为1.5 mg/dL或更低），计划接受心脏手术的患者进行前瞻性评价。术中评估升主动脉粥样硬化（采用主动脉上超声），并根据其严重程度将患者分为3组（正常至轻度、中度和重度）。结果：术后第1天肾功能不全的单因素预测因子是升主动脉粥样硬化（P
Objectives: Renal dysfunction occurring after cardiac operations has been attributed to various factors, but the importance of an atherosclerotic thoracic aorta has not been previously evaluated. The purpose of this study was to identify predictors of postoperative renal dysfunction (50% or more increase from preoperative values) and to evaluate the importance of atherosclerosis of the ascending aorta as a predictor of this complication, Methods: Nine hundred seventy-eight consecutive patients, 50 years of age and older with normal preoperative renal function (serum creatinine level of 1.5 mg/dL or less), who were scheduled to undergo cardiac surgery were prospectively evaluated. Atherosclerosis of the ascending aorta was assessed during the operation (with epiaortic ultrasound), and patients were divided into 3 groups according to its severity (normal-to-mild, moderate, and severe). Results: Univariate predictors of renal dysfunction at postoperative day 1 were atherosclerosis of the ascending aorta (P