Atom-economical chemoselective synthesis of 1,4-diynes and polysubstituted furans/pyrroles from propargyl alcohols and terminal alkynes.
Atom-economical chemoselective synthesis of 1,4-diynes and polysubstituted furans/pyrroles from propargyl alcohols and terminal alkynes.
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DOI：
10.1021/ol201054z
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发表时间：
2011-06
期刊：
影响因子：
5.2
通讯作者：
Tao Wang;Xin-liang Chen;Li Chen;Zhuang-Ping Zhan
中科院分区：
文献类型：
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作者：
Tao Wang;Xin-liang Chen;Li Chen;Zhuang-Ping Zhan
在不同条件下，炔丙醇与末端炔烃的反应导致选择性形成1,4-二炔和多取代呋喃/吡咯。水是1,4-二炔和吡咯选择性合成中唯一的副产物，呋喃合成策略是100%原子经济性。
Under different conditions, the reaction of propargyl alcohols and terminal alkynes leads to the selective formation of 1,4-diynes and polysubstituted furans/pyrroles. Water is the only byproduct in the selective synthesis of 1,4-diynes and pyrroles, and the strategy for the furan synthesis is of 100% atom economy.