The structure and function of adhesive gels from invertebrates
The structure and function of adhesive gels from invertebrates
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DOI：
10.1093/icb/42.6.1164
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发表时间：
2002-12-01
影响因子：
2.6
通讯作者：
Smith, AM
中科院分区：
文献类型：
--
作者：
Smith, AM
许多海洋无脊椎动物使用粘弹性凝胶形成坚固的临时附着物。为了更好地了解这些粘合剂，对已知的凝胶结构和功能进行了分析。有不同的方法来制作凝胶，从缠绕巨型糖蛋白到交联型小蛋白。凝胶的机理在很大程度上取决于聚合物的大小、浓度以及是否交联。与哺乳动物粘液等凝胶相比，粘性粘液凝胶的机制似乎更多地依赖于相对较小的蛋白质，而不是巨型糖蛋白。此外，浓度的变化和特定蛋白质的存在与从非粘连形式到粘连形式的变化有关。不同凝胶在不同浓度下产生的附着强度与活体动物的附着强度的变化进行了比较。这些数据表明，浓度的变化不足以解释粘附性。因此，蛋白质组成的变化可能起到很大的作用。
Many marine invertebrates form strong, temporary attachments using viscoelastic gels. To better understand these adhesives, an analysis of what is known of gel structure and function was performed. There are different ways of making gels, ranging from entangling of giant glycoproteins to crosslinking of smaller proteins. The mechanics of the gel depend largely on the size of the polymer, its concentration, and whether it is crosslinked. Compared to gels such as mammalian mucus, the mechanics of adhesive mucous gels often appear to depend more heavily on relatively small proteins than on megadalton-sized glycoproteins. In addition, changes in concentration and the presence of specific proteins have been associated with the change from a non-adhesive to an adhesive form. The attachment strengths produced by different gels at different concentrations were compared with the changes in attachment strength seen in living animals. These data suggest that changes in concentration are not sufficient to account for adhesion. Thus, it is likely that the changes in protein composition may play a large role.