[Reactive oxygen].

[Reactive oxygen].
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DOI:
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发表时间:
2002
期刊:
Nihon eiseigaku zasshi. Japanese journal of hygiene
影响因子:
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通讯作者:
E. Sato;M. Inoue
E. Sato;M. Inoue
中科院分区:
其他
文献类型:
--
作者:
E. Sato;M. Inoue

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哺乳动物组织中有大量的可利用的三磷酸腺苷,这些三磷酸腺苷是由线粒体中的氧化磷酸化产生的。为了维持身体,需要大量的氧气来再生ATP分子。即使在生理条件下,吸入的氧气中的一小部分也会转化为超氧自由基和相关的代谢物。大多数活性氧物种与各种分子快速反应,从而干扰细胞功能和各种疾病。
Mammalian tissues have large amounts of available ATP which are generated by oxidative phosphorylation in mitochondria. To maintain the body, large amounts of oxygen are required to regenerate the ATP molecules. A small fraction of the inspired oxygen is converted to superoxide radicals and related metabolites even under physiological conditions. Most reactive oxygen species react rapidly with a variety of molecules, thereby interfering with cellular functions and various diseases.