A NEW GLASS-CERAMIC FOR BONE-REPLACEMENT - EVALUATION OF ITS BONDING TO BONE TISSUE
A NEW GLASS-CERAMIC FOR BONE-REPLACEMENT - EVALUATION OF ITS BONDING TO BONE TISSUE
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DOI：
10.1002/jbm.820190608
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发表时间：
1985-01-01
期刊：
影响因子：
--
通讯作者：
ITOO, S
中科院分区：
文献类型：
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作者：
NAKAMURA, T;YAMAMURO, T;ITOO, S
将重量比为MgO，4.6; CaO，44.9; SiO，34.2; PO，16.3; CaF，0.5的玻璃粉末（350目）压制，加热至1050 ℃。在5.degree.并保持在1050 ℃。C持续2 h所得具有氧磷灰石、氟磷灰石和硅灰石晶体的玻璃陶瓷显示出分别为157和1060 MPa [兆帕斯卡]的高弯曲强度和压缩强度。使用兔胫骨评价了这种新型玻璃陶瓷与骨组织的生物相容性和结合能力，并测量了几种陶瓷（新型玻璃陶瓷、致密羟基磷灰石、45 S5生物玻璃、氧化铝陶瓷）与骨组织结合的破坏载荷。新型玻璃陶瓷与骨结合紧密，与致密羟基磷灰石相当，25周时其负荷为骨组织负荷的70%。
Glass powders (350 mesh) of the composition MgO, 4.6; CaO, 44.9; SiO, 34.2; PO, 16.3; CaF, 0.5 in weight ratio were compacted, heated to 1050.degree. C at a rate of 5.degree. C/min and kept at 1050.degree. C for 2 h. The resultant glass-ceramic having oxyapatite, fluoroapatite and wollastonite crystals showed high bending and compressive strengths of 157 and 1060 MPa [megaPascal], respectively. The biocompatibility and bonding ability of this new glass-ceramic to the bone tissue was evaluated using rabbit tibial bones, and the failure load to break the bonding of several ceramics (the new glass-ceramic, dense hydroxyaptite, 45S5 Bioglass, alumina-ceramic) to bone tissues was measured. The new glass-ceramic showed tight bonding to bone comparable with dense hydroxyapaptite, and in 25 wk its load was 70% of that of bone tissue.