Recommendations of the OARSI FDA Osteoarthritis Devices Working Group
Recommendations of the OARSI FDA Osteoarthritis Devices Working Group
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DOI：
10.1016/j.joca.2011.02.017
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发表时间：
2011-05-01
影响因子：
7
通讯作者：
Wright, T.
中科院分区：
文献类型：
--
作者：
Goldberg, V. M.;Buckwalter, J.;Wright, T.
骨关节炎（OA）是最常见的关节炎类型，也是慢性肌肉骨骼疼痛和功能障碍的主要原因。虽然在OA的治疗中建议使用药物和非药物方式，但当髋关节或膝关节OA患者无法获得充分的疼痛缓解和/或功能改善时，应考虑关节置换手术或其他手术干预。全关节置换术是髋关节和膝关节严重OA患者的可靠且具有成本效益的治疗方法。来自队列和观察性研究的证据证实疼痛缓解显著改善，全髋关节（THA）和全膝关节置换术（TKA）后10年的累积翻修率分别为7%和10%。关节置换术已用于大多数滑膜关节，尽管髋关节和膝关节置换术以外的关节的结果并不成功。新器械设计和手术技术的发展突出表明，需要更好地了解不同关节置换术的风险受益比，并确定适当的方法来评价这些设计用于治疗OA关节的新器械的有效性和最佳结局。(C)2011年国际骨关节炎研究学会。由爱思唯尔有限公司出版。保留所有权利。
Osteoarthritis (OA) is the most common type of arthritis and a major cause of chronic musculoskeletal pain and functional disability. While both pharmacologic and non-pharmacologic modalities are recommended in the management of OA, when patients with hip or knee OA do not obtain adequate pain relief and/or functional improvement, joint replacement surgery or other surgical interventions should be considered. Total joint arthroplasties are reliable and cost-effective treatments for patients with significant OA of the hip and knee. Evidence from cohort and observational studies has confirmed substantial improvements in pain relief with cumulative revision rates at 10 years following total hip (THA) and total knee arthroplasties (TKA) at 7% and 10%, respectively. Joint replacements have been used in most every synovial joint, although results for joints other than hip and knee replacement have not been as successful. The evolution of new device designs and surgical techniques highlights the need to better understand the risk to benefit ratio for different joint replacements and to identify the appropriate methodology for evaluating the efficacy and optimal outcomes of these new devices, designed to treat OA joints. (C) 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.