Molecular Design of Heme Proteins for Future Application
Molecular Design of Heme Proteins for Future Application
复制标题
血红素蛋白的分子设计以供未来应用
DOI：
10.1007/s10563-011-9117-9
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发表时间：
2011
影响因子：
3
通讯作者：
Y. Watanabe
中科院分区：
文献类型：
--
作者：
H. Nakajima;O. Shoji;Y. Watanabe
本文综述了近年来人工血红素加氧酶的研究进展。第一个主题是建立在耐热蛋白质上的人工过氧化物酶，其在催化反应中显示出高的热稳定性。在第二个主题中，我们描述了已经开发的将细胞色素P450BSβ转化为多功能加氧酶的“诱饵系统”。
This review surveys our recent studies on artificial heme oxygenases, which consists of two topics. The first topic is an artificial peroxidase founded on a thermally tolerant protein, which shows high thermal stability in the catalytic reaction. In the second topic, we describe ‘Decoy system’ that has been developed to transform Cytochrome P450BSβinto a versatile oxygenase.