Higher-order structure in the trajectories of depression and anxiety following sudden involuntary unemployment.
Higher-order structure in the trajectories of depression and anxiety following sudden involuntary unemployment.
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DOI：
10.1037/a0026243
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发表时间：
2012-05
影响因子：
4.6
通讯作者：
Neiderhiser, Jenae M.
中科院分区：
文献类型：
--
作者：
Howe, George W.;Hornberger, Anna P.;Weihs, Karen;Moreno, Francisco;Neiderhiser, Jenae M.
最近关于共病的研究发现了情绪和焦虑障碍及其症状的等级结构的证据。本研究测试了高阶内化因素是否能解释抑郁和焦虑症状严重程度的变化，以及在经历一段时间的主要生活压力的样本中随时间的变化。研究人员在7个月内从426名最近失业的人身上收集了5次抑郁、慢性担忧和社交焦虑的症状数据。每种症状的生长模型在个体轨迹上发现了显著的差异。不同症状类型的斜率高度相关，截距也是如此。多水平验证性因素分析发现，反映抑郁和焦虑共病的斜率和截距都存在高阶内化因素，内化因素占特定症状集斜率和截距方差的54%至91%，为表征症状水平和变化的一般共同因素和特定领域因素提供了证据。高阶因素的负荷在男性和女性之间略有不同，在比较非裔美国人和白人参与者时也是如此，但在年龄、教育程度或抑郁史方面没有差异。包括性别和抑郁史在内的更远的因素与失业后最初几周的内化密切相关，但内化的变化率与再就业的关系最为密切。研究结果表明，与独立于该因素的焦虑和抑郁的差异相比，压力源可能以不同的方式对共同的内化因素做出贡献。
Recent work on comorbidity finds evidence for hierarchical structure of mood and anxiety disorders and symptoms. This study tests whether a higher-order internalizing factor accounts for variation in depression and anxiety symptom severity and change over time in a sample experiencing a period of major life stress. Data on symptoms of depression, chronic worry and social anxiety were collected 5 times across 7 months from 426 individuals who had recently lost jobs. Growth models for each type of symptom found significant variation in individual trajectories. Slopes were highly correlated across symptom type, as were intercepts. Multilevel confirmatory factor analyses found evidence for a higher-order internalizing factor for both slopes and intercepts, reflective of comorbidity of depression and anxiety, with the internalizing factor accounting for 54% to 91% of the variance in slopes and intercepts of specific symptom sets, providing evidence for both a general common factor and domain-specific factors characterizing level and change in symptoms. Loadings on the higher order factors differed modestly for men and women, and when comparing African-American and White participants, but did not differ by age, education, or history of depression. More distal factors including gender and history of depression were strongly associated with internalizing in the early weeks after job loss, but rates of change in internalizing were associated most strongly with reemployment. Findings suggest that stressors may contribute in different ways to the common internalizing factor as compared to variance in anxiety and depression that is independent of that factor.
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影响因子：
--
作者：
Kendler, KS;Hettema, JM;Prescott, CA
通讯作者：
Prescott, CA
影响因子：
17.7
作者：
Keller, Matthew C.;Neale, Michael C.;Kendler, Kenneth S.
通讯作者：
Kendler, Kenneth S.
影响因子：
3.6
作者：
Cole, JC;Rabin, AS;Kaufman, AS
通讯作者：
Kaufman, AS
影响因子：
3.8
作者：
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通讯作者：
Sousa, Karen H.
影响因子：
6.9
作者：
Davidson, JRT;Miner, CM;Potts, NLS
通讯作者：
Potts, NLS