Respiratory cancer in a cohort of nickel sinter plant workers.
Respiratory cancer in a cohort of nickel sinter plant workers.
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一组镍烧结厂工人罹患呼吸道癌。
DOI：
10.1136/oem.38.4.327
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Mabel Halliday
中科院分区：
文献类型：
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作者：
A. Chovil;And R B SUTHERLAND;Mabel Halliday
对1948年至1962年经营的一家烧结厂的镍精炼厂工人进行了一项研究。通过查阅死亡记录和其他措施，对495名工人进行了全面随访。安大略省工人赔偿委员会所知的事故案件也包括在内。发现54例肺癌和8例鼻窦癌（包括2例随后发展为原发性肺癌的男性）。在工厂运营的早期，肺癌和鼻窦癌的风险要高得多，在运营的第一年，雇员的发病率增加了40%以上。通过标准化道德比（SMR）和标准化发病率比（SIR）的回归检验了剂量-反应关系。SIR指出，暴露在辐射中12个月（早些年为6个月）的风险会翻倍。
A study was undertaken of a cohort of nickel refinery workers from a sinter plant that operated from 1948 to 1962. A complete follow-up of the 495 workers has been carried out by searching death records and other measures. Incidence cases known to the Workmen's Compensation Board of Ontario have been included. Fifty-four cases of lung cancer and eight of sinus cancer (including two in men who subsequently developed primary lung cancer) were located. The risk of lung and sinus cancer was much higher in the earlier days of operation of the plant, with an increase rate of over 40% for those employed in the first year of operation. The dose-response relationship has been examined by regressions of standardised morality ratios (SMR) and standardised incidence ratios (SIR). The SIR suggests that the risk doubled at levels of exposure of 12 months (six months in the earlier years).