Optical and Antibacterial Properties of Chiral Arginine-Stabilized ZnO Nanoparticles.
Optical and Antibacterial Properties of Chiral Arginine-Stabilized ZnO Nanoparticles.
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DOI：
10.1021/acs.langmuir.3c00114
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发表时间：
2023-03
期刊：
影响因子：
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通讯作者：
Yuan Fan;Jun Lin;Zhihua Li;Jiaolong Wang;Junchao Wei
中科院分区：
文献类型：
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作者：
Yuan Fan;Jun Lin;Zhihua Li;Jiaolong Wang;Junchao Wei
纳米粒子表面配体在材料合成、性质和应用中起着重要作用。手性分子是近年来无机纳米粒子性能调控的新热点。本文制备了左旋精氨酸和右旋精氨酸稳定的ZnO纳米粒子，并对其进行了TEM、UV-vis和PL光谱研究，结果表明左旋精氨酸和右旋精氨酸对ZnO纳米粒子的自组装和光致发光性能有不同的影响，表现出明显的手性效应。此外，细胞活性测定、平板计数法和细菌扫描电镜观察结果表明，ZnO@LA的生物相容性低于ZnO@DA，而抗菌效率高于ZnO@DA，表明纳米材料表面的手性分子可能影响其生物学性能。
The surface ligands of nanoparticles (NPs) play essential roles in material synthesis, properties, and applications. Chiral molecules have been the new hot topic in tuning the properties of inorganic NPs. Herein, l-arginine- and d-arginine-stabilized ZnO NPs were prepared, and the TEM, UV-vis, and PL spectra were investigated, which demonstrated that the l-arginine and d-arginine have different effects on the self-assembly and photoluminescence properties of ZnO NPs, showing an evident chiral effect. Furthermore, the results of the cell viability assays, plate counting method, and bacterial SEM images showed that ZnO@LA possessed lower biocompatibility and higher antibacterial efficiency than those of ZnO@DA, implying that the chiral molecules on the surface of nanomaterials may affect their bioproperties.