Selective screening for Chlamydia trachomatis infection in a primary care population of women.
Selective screening for Chlamydia trachomatis infection in a primary care population of women.
复制标题
在初级保健妇女人群中选择性筛查沙眼衣原体感染。
DOI：
10.1093/oxfordjournals.aje.a116840
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发表时间：
1993
影响因子：
5
通讯作者：
Stamm,WE
中科院分区：
文献类型：
--
作者：
Stergachis,A;Scholes,D;Heidrich,FE;Sherer,DM;Holmes,KK;Stamm,WE
在1988年1月1日至1989年6月30日期间，作者利用细胞培养技术评估了沙眼衣原体引起的宫颈感染的流行程度。研究对象为年龄在15至34岁之间的未怀孕妇女，她们曾在华盛顿州西雅图普吉特海湾的两个初级保健诊所就诊。1804名女性中有67名（3.7%）分离出沙眼病，其中13%的女性年龄小于20岁。通过逐步多因素logistic回归分析，7个患者特征是衣原体感染的独立预测因素：未婚、宫颈检查显示宫颈异位、黑人、冲洗、无性、24岁及以下、前一年内有两个或两个以上性伴。在基于风险因素的加权指数上对所有得分为5分或以上的妇女（28%的妇女）进行检测，将检测出77%的感染，阳性预测值为9%。这些结果表明，制定一个基于危险因素的方案来筛查宫颈c感染是可行的。沙眼病患病率低的人群。
The authors used cell cultures to assess the prevalence of cervical infection caused byChlamydia trachomatisin a population-based sample of nonpregnant women aged 15 to 34 years who attended two primary care clinics at Group Health Cooperative of Puget Sound, Seattle, Washington, between January 1, 1988, and June 30, 1989.C. trachomatiswas isolated from 67 of 1,804 women (3.7%), including 13% of those who were less than 20 years of age. Seven patient characteristics were independently predictive of chlamydial infection by stepwise multivariate logistic regression analysis: being unmarried, examination showing cervical ectopy, black race, douching, nulliparity, age of 24 years or less, and intercourse with two or more partners within the preceding year. Testing all women who had a score of 5 or more (28% of women) on a weighted index based on risk factors would detect 77% of all infections with a positive predictive value of 9%. These results suggest that it should be feasible to develop a risk factor-based program to screen for cervical infection withC. trachomatisin populations where its prevalence is low.