Finite Element Modelling and Experimental Validation of the Enamel Demineralisation Process at the Rod Level.
Finite Element Modelling and Experimental Validation of the Enamel Demineralisation Process at the Rod Level.
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DOI：
10.1016/j.jare.2020.08.018
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发表时间：
2021-03
影响因子：
10.7
通讯作者：
Korsunsky AM
中科院分区：
文献类型：
--
作者：
Salvati E;Besnard C;Harper RA;Moxham T;Shelton RM;Landini G;Korsunsky AM
在过去的几年中，人们在利用实验技术观察和表征龋齿方面付出了大量的努力。然而，在潜在脱矿过程的数值模拟方面取得的进展相对较小。本研究首次尝试为牙釉质棒长度尺度的脱矿过程的数值模拟提供简化的计算框架，并通过将数据与实验结果的统计分析进行比较来验证其验证。采用有限元模型来模拟氢离子扩散并导致牙釉质脱矿的时间相关反应扩散方程过程。考虑了羟基磷灰石晶体的局部取向。使用先进的高分辨率同步加速器 X 射线微计算机断层扫描对脱矿前沿进行了实验分析。通过 SEM 和 STEM 成像技术进行了进一步的实验研究。除了建立和验证新的建模框架之外，还深入了解了蚀刻剂溶液 pH 水平的作用。此外，通过模拟不同蚀刻攻角下的脱矿质过程，揭示了不同类型蚀刻图案的起源。这项研究的意义为在不同复杂场景和跨长度尺度范围内模拟牙釉质脱矿铺平了道路。事实上，所提出的框架可以纳入 H 离子以外的化学物质的存在及其扩散和反应，导致羟基磷灰石的溶解和再沉淀。作者的希望和愿望是这项工作最终将有助于确定控制和预防龋齿的新方法。
In the past years, a significant amount of effort has been directed at the observation and characterisation of caries using experimental techniques. Nevertheless, relatively little progress has been made in numerical modelling of the underlying demineralisation process. The present study is the first attempt to provide a simplified calculation framework for the numerical simulation of the demineralisation process at the length scale of enamel rods and its validation by comparing the data with statistical analysis of experimental results. FEM model was employed to simulate a time-dependent reaction-diffusion equation process in which H ions diffuse and cause demineralisation of the enamel. The local orientation of the hydroxyapatite crystals was taken into account. Experimental analysis of the demineralising front was performed using advanced high-resolution synchrotron X-ray micro-Computed Tomography. Further experimental investigations were conducted by means of SEM and STEM imaging techniques. Besides establishing and validating the new modelling framework, insights into the role of the etchant solution pH level were obtained. Additionally, some light was shed on the origin of different types of etching patterns by simulating the demineralisation process at different etching angles of attack. The implications of this study pave the way for simulations of enamel demineralisation within different complex scenarios and across the range of length scales. Indeed, the framework proposed can incorporate the presence of chemical species other than H ions and their diffusion and reaction leading to dissolution and re-precipitation of hydroxyapatite. It is the authors’ hope and aspiration that ultimately this work will help identify new ways of controlling and preventing caries.
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影响因子：
3.9
作者：
Fabregas, Rene;Rubinstein, Jacob
通讯作者：
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影响因子：
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DOI：
10.1016/j.ijmecsci.2018.02.016
发表时间：
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通讯作者：
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作者：
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通讯作者：
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