AgOTf‐Catalyzed Aza‐Diels–Alder Reactions of Danishefsky's Diene with Imines in Water
AgOTf‐Catalyzed Aza‐Diels–Alder Reactions of Danishefsky's Diene with Imines in Water
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DOI：
10.1002/adsc.200390052
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发表时间：
2003-04
影响因子：
5.4
通讯作者：
C. Loncaric;K. Manabe;S. Kobayashi
中科院分区：
文献类型：
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作者：
C. Loncaric;K. Manabe;S. Kobayashi
Danishefsky二烯与亚胺在催化量的三氟甲磺酸银存在下，在水中发生氮杂Diels桤木反应，高产率地得到二氢4吡啶酮。三氟甲磺酸银催化的三组分反应，从醛，胺，和Danishefsky的二烯也有效地进行。在与苯甲醛的三组分反应中，发现添加非离子表面活性剂是有效的。
Aza-Diels–Alder reactions of Danishefsky's diene with imines in water took place smoothly in the presence of a catalytic amount of silver triflate to afford dihydro-4-pyridones in high yields. The silver triflate-catalyzed three-component reactions starting from aldehydes, amines, and Danishefsky's diene were also performed efficiently. In the three-component reactions with benzaldehyde, the addition of a non-ionic surfactant was found to be effective.