The Crisis in Clinical Research: Overcoming Institutional Obstacles
The Crisis in Clinical Research: Overcoming Institutional Obstacles
复制标题
临床研究的危机：克服制度障碍
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
G. Decherney
中科院分区：
文献类型：
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作者：
G. Decherney
阿伦斯教授为每一位与新的科学消费者作斗争的临床科学家写了《临床研究的危机》。凭借临床科学家的技能，Ahrens教授正确地隔离了使成为临床科学家成为一种令人沮丧，乏味，而且往往是情感上痛苦的经历的力量。机会很少，道路是曲折的，“人们对谁在可能不如NIH同行评审严格的过程中获得20亿美元感到难以置信。他说：“在这过程中，很少有休息的机会。根据Ahrens教授的说法，这种新的科学消费者非常重视权宜之计和立竿见影的效果。消费者是一部分普通人，一部分实验室科学家，一部分临床医生，一部分大学管理者，一部分立法者。每一个问题都需要以项目为导向的研究或以疾病为导向的研究来回答。阿伦斯所谓的“基本POR”（以病人为导向的研究）正在消失。他令人信服地认为，研究纯病理生理学将是唯一的方式，
Professor Ahrens has written The Crisis in Clinical Research for every clinical scientist struggling against the new scientific consumer. With the skill of a clinical scientist, Professor Ahrens correctly isolates the forces that have made becoming a clinical scientist a frustrating, tedious, and often emotionally painful experience. The opportunities are few, the path is tortuous, and "The mind boggles at who is getting $2 billion in processes perhaps less rigorous than the peer review of the NIH." there are very few breaks along the way. This new scientific consumer places a high value on expediency and immediate results, according to Professor Ahrens. The consumer is part man-in-the-street, part laboratory scientist, part clinician, part university administrator, part legislator. Each demands answers to either project-oriented research or disease-oriented research. What Ahrens calls "basic POR" (patient-oriented research) languishes. He cogently argues that studying pure pathophysiology will be the only way in which we