Insights into the general and efficient cross McMurry reactions between ketones
Insights into the general and efficient cross McMurry reactions between ketones
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深入了解酮之间一般且有效的麦克默里交叉反应
DOI：
10.1021/jo061644d
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发表时间：
2006-12-22
影响因子：
3.6
通讯作者：
Zhang, Zhan-Bin
中科院分区：
文献类型：
--
作者：
Duan, Xin-Fang;Zeng, Jing;Zhang, Zhan-Bin
二芳基或芳基酮与各种取代酮选择性交叉McMurry偶联的分离收率为53-94%。认为取代基对低价钛表面的强亲和力在调节选择性方面起着重要作用。通过引入这些取代基并在McMurry偶联后去除它们，结构相似的酮类可以有效地交叉偶联。
The selective cross McMurry couplings of diaryl or aryl ketones with various substituted ketones were achieved in 53-94% isolated yields. It is believed that the strong affinity of the substituents to the low-valent titanium surface plays an important role in regards to moderating selectivity. Through the introduction of such substituents followed by their removal post McMurry coupling, structurally similar ketones can be effectively cross-coupled.