Alteration in rate modulation of reflexes to lumbar motoneurons after midthoracic spinal cord injury in the rat. I. Contusion injury.
Alteration in rate modulation of reflexes to lumbar motoneurons after midthoracic spinal cord injury in the rat. I. Contusion injury.
复制标题
大鼠中胸脊髓损伤后腰部运动神经元反射速率调节的变化。
DOI：
10.1089/neu.1998.15.495
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Reier,PJ
中科院分区：
文献类型：
--
作者：
Thompson,FJ;Parmer,R;Reier,PJ
This study investigated the regulation of reflex excitability in normal and midthoracic contusion-injured animals. Recent observations revealed that rate depression, a rate-modulatory process that decreases reflex excitability, was significantly decreased following experimental midthoracic contusion injury. The present experiments were performed to extend those studies and to determine if posttetanic potentiation (PTP), a rate-modulatory process that increases reflex excitability, also was altered in lumbar monosynaptic reflexes (MSRs) following midthoracic contusion injury. In normal animals, a mean PTP of 160% of the pretetanus control was observed at 30 sec following tetanus of the tibial MSR. The decay of the PTP in normal animals followed a rapid initial, then a more gradual pattern, before returning to pretetanus values by 5 min posttetanus. Following midthoracic contusion injury, the maximal (unpotentiated) MSRs were significantly increased in amplitude, whereas the percent potentiation of the PTP of the tibial MSRs was significantly decreased. PTP decay in postcontusion animals was significantly more gradual than observed in normal animals and followed a single decay process. Further analysis of rate depression of tibial MSRs in normal animals revealed that the attenuation pattern produced by stimulation within the lower range of test frequencies was different from that produced by stimulation at the higher test frequencies. Following contusion, rate depression of tibial MSRs was significantly reduced at all test frequencies. These physiological changes in the stretch reflex neural pathway are discussed relative to the development of spasticity.
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猫脊髓中 Ia 和 Ib 传入纤维介导 PAD 通路上节段性和下行传播控制的作用位点。
影响因子：
2.5
作者：
P. Rudomín;I. Jiménez;M. Solodkin;S. Dueñas
通讯作者：
S. Dueñas
观察灰质中神经冲动的相互作用和中枢抑制的性质。
DOI：
10.1152/ajplegacy.1946.146.3.443
发表时间：
1946
期刊：
The American journal of physiology
影响因子：
--
作者：
B. Renshaw
通讯作者：
B. Renshaw
影响因子：
2.5
作者：
ECCLES, JC;WILLIS, WD;SCHMIDT, RF
通讯作者：
SCHMIDT, RF
挫伤和神经组织移植后反射兴奋性的抑制控制。
影响因子：
--
作者：
Thompson,FJ;Reier,PJ;Parmer,R;Lucas,CC
通讯作者：
Lucas,CC
DOI：
10.1085/jgp.38.6.771
发表时间：
1955-07-20
期刊：
The Journal of general physiology
影响因子：
--
作者：
LLOYD DP;McINTYRE AK
通讯作者：
McINTYRE AK