Long-Term Efficacy of Rehabilitation Following Arthroscopic Synovectomy in Patients With Rheumatoid Arthritis Treated With Biologic Agents.
Long-Term Efficacy of Rehabilitation Following Arthroscopic Synovectomy in Patients With Rheumatoid Arthritis Treated With Biologic Agents.
复制标题
关节镜滑膜切除术后康复的长期疗效对用生物学剂治疗的类风湿关节炎患者。
DOI：
10.5535/arm.2017.41.6.998
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发表时间：
2017-12
期刊：
影响因子：
--
通讯作者：
Sekine C
中科院分区：
文献类型：
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作者：
Kanbe K;Sekine C
旨在研究接受生物制剂治疗的类风湿性关节炎患者关节镜滑膜切除术后康复的长期疗效。对17例患者的29个关节进行关节镜下滑膜切除术，分为两组。第1组包括10名患者的19个关节的关节镜滑膜切除术加康复治疗，第2组包括7名患者的10个关节的关节镜滑膜切除术但不进行康复治疗。对关节镜滑膜切除术后 9.7 年的疾病活动评分 C 反应蛋白 (DAS28-CRP)、健康评估问卷-残疾指数 (HAQ-DI) 和功能独立测量 (FIM) 值（运动分量表）进行评估，以确定与结果相关的临床因素。第 1 组的 FIM 评分显着增加 (p=0.05)。第 1 组 9 年时的 HAQ-DI 显着下降 (p=0.02)。因此，关节镜滑膜切除术联合康复对于长期改善 FIM 和 HAQ-DI 评分具有重要意义。 9 年 FIM 评分的多元回归分析表明，康复 (p=0.03) 和疾病持续时间 (p=0.02) 与结果显着相关。 9 年时的 FIM 评分与疾病持续时间显着负相关（p=0.01，r=-0.58，Y=88.89–0.21X）。随着时间的推移，关节镜滑膜切除术后的康复治疗可以有效地帮助类风湿性关节炎患者获得较高的 FIM 评分。
To investigate the long-term efficacy of rehabilitation following arthroscopic synovectomy in patients with rheumatoid arthritis treated with biologic agents. Arthroscopic synovectomy was performed in 29 joints of 17 patients, which were divided into two groups. Group 1 included arthroscopic synovectomy plus rehabilitation for 19 joints in 10 patients, and group 2 included arthroscopic synovectomy without rehabilitation for 10 joints in 7 patients. The Disease Activity Score C-reactive protein (DAS28-CRP), Health Assessment Questionnaire-Disability Index (HAQ-DI), and Functional Independence Measure (FIM) values (motor subscale) at 9.7 years after arthroscopic synovectomy were evaluated to identify the clinical factors related to outcomes. The increase in FIM score was significant in group 1 (p=0.05). HAQ-DI at 9 years was significantly decreased in group 1 (p=0.02). Therefore, arthroscopic synovectomy with rehabilitation was significant in improving FIM and HAQ-DI scores over a long period. Multiple regression analysis of FIM scores at 9 years indicated that rehabilitation (p=0.03) and disease duration (p=0.02) were significantly related to outcomes. FIM score at 9 years was significantly negatively correlated with disease duration (p=0.01, r=−0.58, Y=88.89–0.21X). Rehabilitation following arthroscopic synovectomy was effective in achieving high FIM scores over time in patients with rheumatoid arthritis.