Phenylboronic acid functionalized adsorbents for selective and reversible adsorption of lactulose from syrup mixtures
Phenylboronic acid functionalized adsorbents for selective and reversible adsorption of lactulose from syrup mixtures
复制标题
用于从糖浆混合物中选择性和可逆吸附乳果糖的苯基硼酸功能化吸附剂
DOI：
10.1021/acs.jafc.8b02152
复制
发表时间：
2018
影响因子：
6.1
通讯作者：
Ruijin Yang
中科院分区：
文献类型：
--
作者：
Mingming Wang;Fayin Ye;He Wang;Habtamu Admassu;Yinghui Feng;Xiao Hua;Ruijin Yang
硼酸盐亲和材料已被广泛应用于顺二醇分子的富集化。本工作通过一种简单有效的方法将苯基硼酸基团接枝到氨基大孔树脂上，制备了苯基硼酸功能化吸附剂。元素分析证实了AR-1M和AR-2M的功能化成功，硼的质量分数分别为2.17%和0.73%。在中性条件下(pH=7)，AR-1M具有较高的乳果糖吸附容量(QE-Lu为84.78±0.95 mg/g干树脂)，而AR-2M上引入的戊二醛间隔臂具有良好的吸附选择性(α≈23)、较高的吸附效率(π≈22%)和较快的吸附/脱附速率。通过pH驱动吸附(pH 7-8)和解吸(pH 1.5)可以有效地提高乳果糖(PuDLu)的纯度，这取决于乳果糖与乳糖的比例。当乳果糖/乳糖≥为1：1时，PUDLu≈可达95%。连续重复10次后，INQE-Lu(>；90%)未见明显下降。结果表明，该方法对乳果糖的提纯效果令人满意。
Boronate affinity materials have been widely used for enrichment ofcis-diol molecules. In this work, phenylboronic acid functionalized adsorbents were prepared via a simple and efficient procedure grafting phenylboronic acid groups onto amino macroporous resins. Elemental analysis has confirmed the successful functionalization of AR-1M and AR-2M with approximately 2.17% and 0.73% weight percentage of boron. Comparatively, AR-1M possessed higher lactulose adsorption capacity (qe-Lu, 84.78 ± 0.95 mg/g dry resin) under neutral conditions (pH = 7), while the introduced glutaraldehyde spacer arms on AR-2M resulted in excellent adsorption selectivity (α ≈ 23), high adsorption efficiency (π ≈ 22%), and fast adsorption/desorption rate. The purity of lactulose (PuDLu) through pH-driven adsorption (pH 7–8) and desorption (pH 1.5) can be effectively improved depending on the ratio of lactulose to lactose. When lactulose/lactose ≥ 1:1, PuDLu≈ 95% was achieved. No significant drop inqe-Lu(>90%) was observed after ten-consecutive repeats. Results demonstrated that the newly developed method may achieve satisfactory performance in lactulose purification.