Bright light therapy decreases winter binge frequency in women with bulimia nervosa: A double-blind, placebo-controlled study

Bright light therapy decreases winter binge frequency in women with bulimia nervosa: A double-blind, placebo-controlled study
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DOI:
10.1016/s0010-440x(99)90088-3
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发表时间:
1999-11-01
影响因子:
7.3
通讯作者:
Halmi, KA
Halmi, KA
中科院分区:
医学2区
文献类型:
--
作者:
Braun, DL;Sunday, SR;Halmi, KA

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本研究的目的是确定冬季强光疗法对神经性贪食症受试者的暴饮暴食和腹泻频率以及抑郁症状的影响。34名女性暴食症门诊患者在冬季接受10,000勒克斯明亮白色光或50勒克斯昏暗红光(安慰剂对照)治疗。在这项双盲研究中,安慰剂组(n = 18)和强光组(n = 16)在年龄、季节性程度(通过季节模式评估问卷[SPAQ]测量),以及并发抑郁症(通过DSM-IV [SCID]的结构化临床访谈测量),基线数据收集3周后,进行3周的每日半小时晨间光照治疗和2周的随访评估。存在显著的光处理与时间的相互作用(Wilks λ = 0.81,F(2,28)= 3,31,P = 0.05)。与安慰剂组相比,强光组从基线到治疗结束的平均狂欢频率下降幅度更大(F(1,29)= 6.41,P = 0.017)。抑郁水平(通过每日贝克抑郁量表[BDI]评分测量)在任何阶段在组间没有显著差异,并且抑郁和季节性都不影响对光处理的反应。在该双盲研究中,接受3周冬季强光治疗的暴食症妇女报告,与接受昏暗日光治疗的受试者相比,红灯版权所有(C)1999 W.B.桑德斯公司
The study objective was to determine the effect of winter bright light therapy on binge and purge frequencies and depressive symptoms in subjects with bulimia nervosa. Thirty-four female bulimic outpatients were treated with either 10,000 lux bright white light or 50 lux dim red light (placebo control) during the winter months. In this double-blind study, the placebo group (n = 18) and the bright light group (n = 16) were matched for age, degree of seasonality (measured by the Seasonal Patterns Assessment Questionnaire [SPAQ]), and concurrent depression (measured by Structured Clinical Interview for DSM-IV [SCID]), Three weeks of baseline data collection were followed by 3 weeks of half-hour daily morning light treatment and 2 weeks of follow-up evaluation. There was a significant light-treatment by time interaction (Wilks' lambda = .81, F(2,28) = 3,31, P = .05). The mean binge frequency decreased significantly more from baseline to the end of treatment for the bright light group (F(1,29) = 6.41, P = .017) than for the placebo group. The level of depression (measured by daily Beck Depression Inventory [BDI] scores) did not significantly differ between the groups during any phase, and neither depression nor seasonality affected the response to light treatment, In this double-blind study, bulimic women who received 3 weeks of winter bright light treatment reported a reduced binge frequency between baseline and the active treatment period in comparison to subjects receiving dim red light. Copyright (C) 1999 by W.B. Saunders Company.