Staff beliefs about drug abuse clinical trials
Staff beliefs about drug abuse clinical trials
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DOI：
10.1016/s0740-5472(02)00238-6
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发表时间：
2002-07-01
影响因子：
3.9
通讯作者：
Weinstein, S
中科院分区：
文献类型：
--
作者：
Forman, RF;Bovasso, G;Weinstein, S
来自国家药物滥用临床试验网络中10个社区成瘾治疗组织的工作人员参加了一次关于成瘾研究实践和人体主体保护的教育会议。这个1.5小时的报告涉及“知情同意”、“研究信息的机密性”、“纳入和排除标准”、“随机分配”、“患者保护”和“患者支付”。对115名工作人员进行会前和会后调查，以衡量他们对临床试验的信念。在基线时，52%的工作人员认为，即使患者表现不佳，他们也可以退出研究，55%的工作人员认为他们有权这样做；44%的工作人员同意，患者可以参与临床试验，而不知道研究中会发生什么。在教育会议结束后，工作人员对患者保护的信念在七个项目中的五个项目上显著增加。四分之一的工作人员仍然认为向患者支付费用是有害的，37%的人不认为参与临床试验会增加患者康复的机会。(C)2002 Elsevier Science Inc.保留所有权利。
Staff from 10 community-based addiction treatment organizations in the National Drug Abuse Clinical Trials Network participated in an educational session about addiction research practices and human subject protections. This 1.5-hour presentation addressed "informed consent," "confidentiality of research information," "inclusion and exclusion criteria," "random assignment," "patient protections," and "patient payments." Pre- and postsession surveys were administered to 115 staff members measuring their beliefs about clinical trials. At baseline, 52% of staff believed patients could transfer out of a study even if they were doing poorly, and 55% believed staff had this right; 44% agreed that patients could participate in a clinical trial without understanding what would take place in the study. After the educational session, staff beliefs about patient protections were significantly increased in five of the seven items. A fourth of staff continued to believe patient payments were harmful, and 37% did not believe participation in a clinical trial would increase a patient's chances at recovery. (C) 2002 Elsevier Science Inc. All rights reserved.