Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders

Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders
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DOI:
10.1016/j.rasd.2010.03.006
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发表时间:
2011-01-01
影响因子:
2.5
通讯作者:
Oswald, D. P.
Oswald, D. P.
中科院分区:
医学3区
文献类型:
--
作者:
Mazefsky, C. A.;Kao, J.;Oswald, D. P.

文献摘要

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本研究探讨了自我报告措施的效用,以筛选自闭症谱系障碍(ASD)的精神共病。38名10-17岁的ASD患者完成了儿童抑郁量表-简短版(CDI-S)、修订的儿童明显焦虑量表(RCMAS)、Conners-Wells青少年自我报告量表-简短版(CASS-S)和简短的莱顿强迫量表-儿童版(SLOI-CV)。他们的父母接受了自闭症患者现在和终身访谈(ACI-PL),以确定精神病诊断。计算每个自我报告的敏感性、特异性、阳性和阴性预测值以及可靠性系数,并与文献中的值进行比较。CDI-S和CASS-S产生了大量的假阴性,样本中的灵敏度和特异性低于文献。有焦虑和无焦虑的参与者之间的总平均RCMAS评分几乎有显著差异,尽管两组的平均值都低于关注阈值。SLOI-CV的假阳性率较高。所有四种仪器的可靠性系数与文献值相当。由于样本量的原因,结果必须被视为初步结果。然而,研究结果表明,虽然自我报告的工具可以提供有用的信息,在ASD的精神共病的诊断,必须谨慎的解释。(C)2011爱思唯尔有限公司保留所有权利。
This study investigated the utility of self-report measures to screen for psychiatric comorbidities in autism spectrum disorders (ASDs). Thirty-eight 10-17 year olds with an ASD and without mental retardation completed: the Children's Depression Inventory-Short version (CDI-S), Revised Children's Manifest Anxiety Scale (RCMAS), Conners-Wells Adolescent Self-report Scale-Short edition (CASS-S), and Short Leyton Obsessional Inventory-Child Version (SLOI-CV). Their parents were interviewed with the Autism Comorbidity Interview-Present and Lifetime (ACI-PL) to establish psychiatric diagnoses. Sensitivity, specificity, positive and negative predictive values, and reliability coefficients were calculated for each self-report and compared to values from literature. The CDI-S and CASS-S yielded a high number of false negatives, with lower sensitivities and specificities in the sample than the literature. There was a nearly significant difference in total mean RCMAS scores between participants with and without anxiety, though again the means for both groups were below the threshold of concern. The SLOI-CV yielded a high false positive rate. All four instruments had reliability coefficients comparable to literature values. Results must be considered preliminary due to sample size. However, the findings suggest that although self-report instruments may provide useful information in the diagnosis of psychiatric comorbidities in ASD, caution must be exercised in their interpretation. (C) 2011 Elsevier Ltd. All rights reserved.