Widespread losses of vomeronasal signal transduction in bats.

Widespread losses of vomeronasal signal transduction in bats.
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蝙蝠犁鼻信号转导广泛丧失。

DOI:
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发表时间:
2011
影响因子:
10.7
通讯作者:
Jianzhi Zhang
Jianzhi Zhang
中科院分区:
生物学1区
文献类型:
--
作者:
Huabin Zhao;Dong Xu;Shuyi Zhang;Jianzhi Zhang

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脊椎动物犁鼻系统(VNS)检测种内信息素和环境气味。我们对代表翼翅目(翼手目(蝙蝠)的两个亚目之一)所有主要基础谱系的 11 个物种中编码 Trpc2 的基因片段进行了测序,Trpc2 是犁鼻信号转导至关重要的离子通道。我们的序列显示 Trpc2 在 11 只蝙蝠中都是假基因,这表明所有的阴翅手足类动物都缺乏犁鼻敏感性。蝙蝠的另一个亚目羊翅目(Yangochiroptera)四种物种的 Trpc2 序列表明,一些但不是所有羊翅目动物的犁鼻不敏感。这些结果与蝙蝠 VNS 的可用形态学数据一起强烈表明,蝙蝠犁鼻信号转导和敏感性存在多种且广泛的损失。未来对少数仍保留 VNS 的蝙蝠的 V​​NS 特定功能进行仔细研究可能有助于解释为什么它在大多数蝙蝠中是可有可无的。
The vertebrate vomeronasal system (VNS) detects intraspecific pheromones and environmental odorants. We sequenced segments of the gene encoding Trpc2, an ion channel crucial for vomeronasal signal transduction, in 11 species that represent all main basal lineages of Yinpterochiroptera, one of the two suborders of the order Chiroptera (bats). Our sequences show that Trpc2 is a pseudogene in each of the 11 bats, suggesting that all yinpterochiropterans lack vomeronasal sensitivity. The Trpc2 sequences from four species of Yangochiroptera, the other suborder of bats, suggest vomeronasal insensitivity in some but not all yangochiropterans. These results, together with the available morphological data from the bat VNS, strongly suggest multiple and widespread losses of vomeronasal signal transduction and sensitivity in bats. Future scrutiny of the specific functions of the VNS in the few bats that still retain the VNS may help explain why it is dispensable in most bats.
DOI: 10.1093/molbev/msn107
发表时间: 2008-08-01
影响因子: 10.7
作者:
Grus, Wendy E.;Zhang, Jianzhi
通讯作者: Zhang, Jianzhi