Misoprostol as the primary agent for medical abortion in a low-income urban setting
Misoprostol as the primary agent for medical abortion in a low-income urban setting
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DOI：
10.1016/j.contraception.2004.03.007
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发表时间：
2004-08-01
期刊：
影响因子：
2.9
通讯作者：
Chen, A
中科院分区：
文献类型：
--
作者：
Borgatta, L;Mullally, B;Chen, A
本研究的目的是评估市中心一家医院流产服务中以米索前列醇为主要药物的早期药物流产的结局。这是从2001年7月到2002年12月的回顾性图表回顾。如果经阴道超声检查妊娠期小于或等于8周，且无医学禁忌症，则妇女有资格获得该项服务。两剂800马克米索前列醇阴道给药，间隔24小时。初步随访安排在2-3天后。在440名接受药物流产的妇女中，373名（90.8%，95%可信区间（CI） 88-94%）完成了药物流产，38名（9.2%）有子宫抽吸，其余的没有随访或没有随访。11例有医学指征，指征率为2.7%。胎龄、年龄、妊娠、胎次、既往流产史、种族和支付者与总体误吸率或随访率无显著相关，但胎龄与医学指征误吸相关。在报告组织传代时间的57名妇女中，从初始米索前列醇剂量开始的平均时间为8.5小时（95%可信区间为6.5-13小时）。版权所有。
The purpose of this study was to assess the outcomes of early medical abortion in an inner-city hospital abortion service, using misoprostol as the primary agent. This was a retrospective chart review from July 2001 through December 2002. Women were eligible if they had a viable pregnancy with gestational age 8 weeks or less by transvaginal ultrasound and no medical contraindications. Two doses of 800 mug misoprostol were administered vaginally, 24 h apart. Initial follow-up was scheduled 2-3 days later. Of the 440 women who underwent medical abortion, 373 (90.8%, 95% confidence interval (CI) 88-94%) completed abortion medically, 38 (9.2%) had uterine aspiration and the remainder had incomplete or no follow-up. Of uterine aspirations, 11 were medically indicated, giving a rate of indicated aspiration of 2.7%. Gestational age, age, gravidity, parity, past abortion history, ethnic group and payer did not significantly correlate with overall rate of aspiration or rate of follow-up, but gestational age was correlated with medically indicated aspiration. Among 57 women who reported a time of tissue passage, the mean time from initial misoprostol dose was 8.5 h (95% CI 6.5-13 h). (C) 2004 Elsevier Inc. All rights reserved.