Mouse studies on inhibitors of Plasmodium falciparum Hsp90: progress and challenges

Mouse studies on inhibitors of Plasmodium falciparum Hsp90: progress and challenges
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DOI:
10.1017/s0031182014000754
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发表时间:
2014-08-01
期刊:
影响因子:
2.4
通讯作者:
Pillai, Dylan R.
Pillai, Dylan R.
中科院分区:
医学2区
文献类型:
--
作者:
Bayih, Abebe Genetu;Pillai, Dylan R.

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本综述重点介绍了在小鼠模型中进行的研究,以评估针对疟疾热休克蛋白 (Hsp) 90 的化合物的功效。所取得的进步和存在的局限性都得到了强调。
This review highlights studies conducted in murine models to evaluate the efficacy of compounds targeting Heat shock protein (Hsp) 90 of malaria. Both advances achieved and limitations that exist are highlighted.