Age-related changes in rhythmically bursting activity in the medial septum of rats
Age-related changes in rhythmically bursting activity in the medial septum of rats
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DOI：
10.1016/s0006-8993(00)02571-3
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发表时间：
2000-09-08
期刊：
影响因子：
2.9
通讯作者：
Bassant, MH
中科院分区：
文献类型：
--
作者：
Apartis, E;Poindessous-Jazat, F;Bassant, MH
老化的影响发射:septohippocampal神经元的估计在被麻醉,克制年轻,老了,很老的老鼠(分别为3、23和30个月)。在不同的觉醒状态下获得细胞外记录。整个神经元群的平均自发活动不受年龄的影响。相比之下，老年大鼠节律性破裂神经元的比例明显较低。在清醒状态下，老龄大鼠和超龄大鼠的爆发活动明显减少(P
The effects of aging on the firing: of septohippocampal neurons were estimated in unanesthetized, restrained young, old and very old rats (respectively 3, 23 and 30 months). Extracellular recordings were obtained during various states of arousal. The mean spontaneous activity for the overall neuronal population was not modified by aging. In contrast, the percentage of rhythmically bursting neurons was significantly lower in aged rats. During wakefulness, decrease of bursting activity was observed in old and very old rats (P