Neural response properties of primary, rostral, and rostrotemporal core fields in the auditory cortex of marmoset monkeys
Neural response properties of primary, rostral, and rostrotemporal core fields in the auditory cortex of marmoset monkeys
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DOI：
10.1152/jn.00884.2007
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发表时间：
2008-08-01
影响因子：
2.5
通讯作者：
Wang, Xiaoqin
中科院分区：
文献类型：
--
作者：
Bendor, Daniel;Wang, Xiaoqin
灵长类听觉皮层的核心区包含一个初级区和两个初级区（AI，初级听觉皮层; R，吻侧区; RT，吻颞区）。虽然这是合理的假设，多个核心领域提供了一个优势，听觉处理一个单一的主要领域，这些领域发挥的不同作用，以及它们是否共同形成一个功能通路，如处理频谱或时间信息是未知的。在这份报告中，我们比较了清醒的绒猴（Callithrix jacchus）的纯音和正弦振幅调制音的三个核心领域的神经元的反应特性。主要意见如下。(1)所有这三个领域都对频谱窄带声音做出响应，并且是音调拓扑组织的。(2)（3）RT区神经元的最佳声级低于AI区和R区神经元。此外，RT域中的速率-水平函数比AI和R域中的速率-水平函数更普遍地具有非单调性。(4)RT和R野的神经元比AI野的神经元具有更长的最小潜伏期。(5)场RT和R对调幅音的刺激同步性比场AI差。(6)在三个核心领域之间，更喙区域（R和RT）具有比AI更窄的基于发射率的调制传递函数。这种效应只在非同步神经元中观察到。同步的神经元则没有这种趋势。
The core region of primate auditory cortex contains a primary and two primary-like fields (AI, primary auditory cortex; R, rostral field; RT, rostrotemporal field). Although it is reasonable to assume that multiple core fields provide an advantage for auditory processing over a single primary field, the differential roles these fields play and whether they form a functional pathway collectively such as for the processing of spectral or temporal information are unknown. In this report we compare the response properties of neurons in the three core fields to pure tones and sinusoidally amplitude modulated tones in awake marmoset monkeys (Callithrix jacchus). The main observations are as follows. (1) All three fields are responsive to spectrally narrowband sounds and are tonotopically organized. (2) Field AI responds more strongly to pure tones than fields R and RT. (3) Field RT neurons have lower best sound levels than those of neurons in fields AI and R. In addition, rate-level functions in field RT are more commonly nonmonotonic than in fields AI and R. (4) Neurons in fields RT and R have longer minimum latencies than those of field AI neurons. (5) Fields RT and R have poorer stimulus synchronization than that of field AI to amplitude-modulated tones. (6) Between the three core fields the more rostral regions (R and RT) have narrower firing-rate-based modulation transfer functions than that of AI. This effect was seen only for the nonsynchronized neurons. Synchronized neurons showed no such trend.