Racial Differences in the Use and Outcome of Neoadjuvant Chemotherapy for Breast Cancer: Results From the National Cancer Data Base

Racial Differences in the Use and Outcome of Neoadjuvant Chemotherapy for Breast Cancer: Results From the National Cancer Data Base
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DOI:
10.1200/jco.2015.63.7801
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发表时间:
2015-12-20
影响因子:
45.3
通讯作者:
Lannin, Donald R.
Lannin, Donald R.
中科院分区:
医学1区
文献类型:
--
作者:
Killelea, Brigid K.;Yang, Vicky Q.;Lannin, Donald R.

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PurposeTo explore racial differences in the use and outcome of neoadjuvant chemotherapy for breast cancer.MethodsThe National Cancer Data Base被查询,以确定在2010年和2011年诊断为1 - 3期乳腺癌的女性。化疗的使用和病理完全反应(pCR)率确定为各种种族/ethnic groups.ResultsOf 278,815例已知的种族和民族,127,417(46%)接受化疗,和121,446化疗的时间是已知的,27,300(23%)接受新辅助化疗。化疗,尤其是新辅助化疗,在黑人、西班牙裔和亚裔女性中比在白色女性中更常见(P
PurposeTo explore racial differences in the use and outcome of neoadjuvant chemotherapy for breast cancer.MethodsThe National Cancer Data Base was queried to identify women with stage 1 to 3 breast cancer diagnosed in 2010 and 2011. Chemotherapy use and rate of pathologic complete response (pCR) was determined for various racial/ethnic groups.ResultsOf 278,815 patients with known race and ethnicity, 127,417 (46%) received chemotherapy, and of 121,446 where the timing of chemotherapy was known, 27,300 (23%) received neoadjuvant chemotherapy. Chemotherapy, and neoadjuvant chemotherapy in particular, was given more frequently to black, Hispanic, and Asian women than to white women (P