The fine structure of the rod-bipolar cell synapse in the retina of the albino rat.
The fine structure of the rod-bipolar cell synapse in the retina of the albino rat.
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DOI：
10.1083/jcb.4.4.459
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发表时间：
1958-07-25
期刊：
影响因子：
--
通讯作者：
LADMAN AJ
中科院分区：
文献类型：
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作者：
LADMAN AJ
的杆双极突触的精细结构的描述和说明。每个杆状小球具有约0.5 × 2.0微米的大的、单个的、椭圆形或细长的球体。围绕着细胞核的是无颗粒内质网的成分。双极树突伸入小球体的下极，通常终止于两个被裂缝分开的裂片。突触区域的质膜致密且较厚。在杆状小球细胞质中，与质膜邻接的是一个致密的、略凹的弓形结构，杆状弓形致密物从双极双极突起的基部通过裂隙延伸到对侧的等同点。同样在小球内，并且在杆弧形密度的外部（朝向巩膜），是平行的、致密的、薄的板层，杆突触板层。其厚度约为25 mµ，最宽处的宽度约为400 mµ。这个半月形的板横跨在双极突的两个叶之间的裂缝。薄片似乎由直径为5至7 mµ的短的规则小棒或圆柱体组成，其长轴垂直于薄片平面。在视杆小球和双极终末的细胞质中发现的微小胞质小泡在视杆突触板层附近最为丰富。
The fine structure of the rod-bipolar synapse is described and illustrated. Each rod spherule possesses a large, single, oval or elongate mitochondrion approximately 0.5 x 2.0 microns. Surrounding the mitochondrion are elements of agranular endoplasmic reticulum. The bipolar dendrite projects into the lower pole of the spherule and usually terminates in two lobes separated by a cleft. The plasma membranes appear dense and thicker in the region of the synapse. In the rod spherule cytoplasm, contiguous with the plasma membrane is a dense, slightly concave arciform structure, the rod arciform density, extending from the base of the bipolar bifid process through the cleft to an equivalent point on the opposite side. Also within the spherule, and external (towards the sclera) to the rod arciform density, is a parallel, dense, thin lamella, the rod synaptic lamella. This is approximately 25 mµ in thickness and 400 mµ in width at its widest extent. This halfmoon-shaped plate straddles the cleft between the two lobes of the bipolar process. The lamella appears to consist of short regular rodlets or cylinders 5 to 7 mµ in diameter, oriented with their long axes perpendicular to the plane of the lamella. Minute cytoplasmic vesicles found in the cytoplasm of both the rod spherule and the bipolar terminal are most abundant near the rod synaptic lamella.